1
Daniel H Appella, Christopher Micklitsch: Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens. The United States of America represented by the Secretary Department of Health and Human Services, Leydig Voit & Mayer, October 13, 2015: US09156778

Disclosed is a method for lowering the detection limit in a method of detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA with a substrate having a second PNA affixed thereto, the second PNA comprising at least one trans-cyclopentane residue, wherein the first PNA ha ...


2
Daniel H Appella, Christopher Micklitsch: Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens. May 3, 2012: US20120107794-A1

The present invention concerns methods for detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA having a first cross-reactive functional group with a substrate having a second PNA affixed thereto, the second PNA having a second first cross-reactive functional group, w ...


3
Daniel H Appella, Christopher Micklitsch: Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens. December 20, 2012: US20120322053-A1

The present invention concerns methods for detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA having a first cross-reactive functional group with a substrate having a second PNA affixed thereto, the second PNA having a second first cross-reactive functional group, w ...



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