1
Christopher E Szymczak, James T Walter: Simethicone solid oral dosage form. McNeil PCC, Timothy E Tracy, September 5, 2006: US07101573 (40 worldwide citation)

The present invention provides a composition for forming a compressed solid dosage form that is a free-flowing compressible admixture of simethicone, an adsorbant, and an optional active agent, wherein the weight ratio of simethicone to adsorbent is at least 1:2.22. Also included are solid dosage fo ...


2
Jen Chi Chen, Harry S Sowden, Joseph R Luber, Leo B Kriksunov, Frank J Bunick, Christopher E Szymczak, Gregory E Koll: Manufacture of lozenge product with radiofrequency. McNeil PPC, William E McGowan, January 1, 2013: US08343533 (6 worldwide citation)

The present invention features a process for making a lozenge product including the steps of forming a powder blend containing an amorphous carbohydrate polymer into the desired shape of the lozenge product and applying radiofrequency energy to the shape for a sufficient period of time to soften or ...


3
Harry S Sowden, Frank J Bunick, Joseph R Luber, Leo B Kriksunov, Christopher E Szymczak: Machine for the manufacture of dosage forms utilizing radiofrequency energy. McNeil PPC, William E McGowan, August 19, 2014: US08807979 (3 worldwide citation)

The present invention features the present invention features a machine for the production of a solid dosage form including: (a) a die platen having one or more forming cavities each having an inner wall, a first opening at the surface of one side of the die platen, and a second opening at the surfa ...


4
Christopher E Szymczak, Frank J Bunick, Harry S Sowden, Joseph R Luber, Leo B Kriksunov: Manufacture of variable density dosage forms utilizing radiofrequency energy. McNeil PPC, William E McGowan, October 14, 2014: US08858210 (3 worldwide citation)

The present invention features the present invention features a tablet including at least one pharmaceutically active ingredient, wherein the shape of said tablet includes at least one major face wherein: (i) the peak penetration resistance at the perimeter of said major face of the tablet is at lea ...


5
Jen Chi Chen, Harry S Sowden, Joseph R Luber, Leo B Kriksunov, Frank J Bunick, Christopher E Szymczak, Gregory E Koll: Manufacture of lozenge product with radiofrequency. McNeil PPC, William E McGowan, October 21, 2014: US08865204 (2 worldwide citation)

The present invention features a process for making a lozenge product including the steps of forming a powder blend containing an amorphous carbohydrate polymer into the desired shape of the lozenge product and applying radiofrequency energy to the shape for a sufficient period of time to soften or ...


6
Frank J Bunick, Harry S Sowden, Joseph R Luber, Leo B Kriksunov, Christopher E Szymczak: Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder. McNeil PPC, William E McGowan, October 28, 2014: US08871263 (2 worldwide citation)

The present invention features a process for making a tablet by (i) compacting a powder blend in a die to form a tablet shape, wherein the powder blend contains a pharmaceutically active agent and a meltable binder and (ii) applying radiofrequency energy to the tablet shape for a sufficient period o ...


7
Harry S Sowden, Frank J Bunick, Joseph R Luber, Leo B Kriksunov, Christopher E Szymczak: Machine for the manufacture of dosage forms utilizing radiofrequency energy. McNeil PPC, William E McGowan, August 18, 2015: US09107807 (1 worldwide citation)

The present invention features the present invention features a machine for the production of a solid dosage form including: (a) a die platen having one or more forming cavities each having an inner wall, a first opening at the surface of one side of the die platen, and a second opening at the surfa ...


8
Christopher E Szymczak: Film forming compositions containing sucralose. McNeil PPC, November 13, 2012: US08309118

Water soluble, gelatin-free dip coatings for substrates comprising a hydrocolloid, such as carrageenan, and sucralose.


9
Jen Chi Chen, Kenneth Day, Christopher E Szymczak: Orally disintegrating tablet. Johnson & Johnson Consumer, December 6, 2016: US09511028

The present invention features a tablet containing at least one first material, at least one second material, and at least one pharmaceutically active agent, wherein: (a) the first material is a dielectric water-containing material (i) containing from about 1 to about 5 percent, by weight, of bound ...


10
Frank J Bunick, Harry S Sowden, Joseph R Luber, Leo B Kriksunov, Christopher E Szymczak: Manufacture of tablet in a die utilizing powder blend containing water-containing material. Johnson & Johnson Consumer, April 4, 2017: US09610224

The present invention features the present invention features a process for making a tablet by compacting a powder blend in a die platen to form a tablet shape, wherein the powder blend includes a pharmaceutically active agent and a water-containing material, and applying energy to the tablet shape ...