1
Eric R Diebold, Richard J Kordal, Nigel A Surridge, Christopher D Wilsey: Electrochemical sensor. Boehringer Mannheim Corporation, D Michael Young, Max J Kenemore, Marilyn L Amick, August 1, 1995: US05437999 (641 worldwide citation)

A method for fabricating high-resolution, biocompatible electrodes is disclosed, allowing production of an electrochemical sensor which is capable of precise analyte concentration determination on a very small sample size. Electrically conducting material is affixed to a first insulating substrate. ...


2
Zhi D Deng, Gerald F Sigler, Nigel A Surridge, Christopher D Wilsey, Robert J McEnroe, Walter W Jernigan, Rebecca W Muddiman: Osmium-containing redox mediator. Boehringer Mannheim Corporation, D Michael Young, Max J Kenemore, Marilyn L Amick, December 31, 1996: US05589326 (297 worldwide citation)

A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solu ...


3
Zhi David Deng, Gerald F Sigler, Nigel A Surridge, Christopher D Wilsey, Robert J McEnroe, Walter W Jernigan, Rebecca W Muddiman: Reagent including an osmium-containing redox mediator. Boehringer Mannheim Corporation, D Michael Young, Max J Kenemore, Brent A Harris, December 8, 1998: US05846702 (210 worldwide citation)

A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solu ...


4
Christopher D Wilsey: Electrodes, methods, apparatuses comprising micro-electrode arrays. Roche Diagnostics Operations, Corange International, Woodard Emhardt Moriarty McNett & Henry, October 2, 2007: US07276146 (173 worldwide citation)

Described are micro-arrays of electrodes disposed proximal to a flexible substrate, electronic components and sensors comprising such arrays, and methods of use for such arrays.


5
Christopher D Wilsey: Method for determining the concentration of an analyte in a liquid sample using small volume samples and fast test times. Roche Diagnostics Operations, Corange International, Woodard Emhardt Moriarty McNett & Henry, October 2, 2007: US07276147 (158 worldwide citation)

Analytes in a liquid sample are determined by methods utilizing sample volumes of less than about 1.5 μl and test times within ten seconds. The methods are preferably performed using small test strips including a sample receiving chamber filled with the sample by capillary action.


6
Raghbir S Bhullar, Christopher D Wilsey, Brian S Hill: Biosensor. Roche Diagnostics Operations, Jill L Woodburn, Justin Sage, October 30, 2007: US07287318 (126 worldwide citation)

A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess circumscribes at least a portion of t ...


7
Raghbir S Bhullar, Christopher D Wilsey, Brian S Hill: Biosensor. Roche Diagnostics Corporation, Jill L Woodburn, November 11, 2003: US06645359 (102 worldwide citation)

A biosensor is provided that comprises a plate element with a pre-determined reaction zone and a recess positioned adjacent to the reaction zone. The biosensor also comprises a reagent that is positioned on the reaction zone. In preferred embodiments, the recess circumscribes at least a portion of t ...


8
Raghbir S Bhullar, Christopher D Wilsey, Brian S Hill: Biosensor. Roche Diagnostics Corporation, Jill Woodburn, September 10, 2002: US06447657 (86 worldwide citation)

A biosensor is provided that includes first and second plate elements, wherein each plate elements has first and second ends and first and second lateral borders. In addition, the biosensor includes a spacer positioned to lie between the first and second plate elements so that at least a portion of ...


9
Raghbir S Bhullar, John T Austera, Brian S Hill, Christopher D Wilsey: Biosensor. Roche Diagnostics Corporation, Jill L Woodburn, July 27, 2004: US06767440 (52 worldwide citation)

A biosensor is provided in accordance with the present invention. The biosensor includes an electrode support substrate, electrodes positioned on the electrode support substrate, a sensor support substrate coupled to the electrode support substrate, and electrically conductive tracks positioned on t ...


10
Raghbir S Bhullar, Christopher D Wilsey, Jeffrey N Shelton: Capillary hematocrit separation structure and method. Roche Diagnostics Corporation, Brinks Hofer Gilson & Lione, November 20, 2001: US06319719 (25 worldwide citation)

A capillary hematocrit separation structure is included within a housing having a fluid inlet port, a reaction region, and a capillary pathway connecting the inlet port and the reaction region. The capillary pathway is dimensioned so that the driving force for the movement of liquid through the capi ...