1
Dosuk D Lee, Christian Rey, Maria Aiolova: Bioresorbable ceramic composites. Etex Corporation, Clark & Elbing, February 22, 2000: US06027742 (234 worldwide citation)

A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The poorly crystalline apatitic calcium phosphate is characterized in that, when placed in an intramuscular or subcutaneous site, resorption of a ...


2
Dosuk D Lee, Christian Rey, Maria Aiolova: Preparation of cell seeded ceramic compositions. Etex Corporation, Mary Rose Scozzafava, Clark & Elbing, October 31, 2000: US06139578 (180 worldwide citation)

The present invention provides a synthetic, poorly-crystalline apatitic (PCA) calcium phosphate material seeded with cells. Preferably, the cells are tissue-forming or tissue-degrading cells. The compositions provided by the present invention are useful for a variety of applications, including in vi ...


3
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Bioresorbable ceramic composites. Etex Corporation, Hale and Dorr, December 18, 2001: US06331312 (175 worldwide citation)

A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The poorly crystalline apatitic calcium phosphate is characterized in that, when placed in an intramuscular or subcutaneous site, resorption of a ...


4
Dosuk D Lee, Christian Rey, Maria Aiolova: Cartilage growth from cell seeded ceramic compositions. Etex Corporation, Clark & Elbing, August 21, 2001: US06277151 (165 worldwide citation)

The present invention provides a synthetic, poorly-crystalline apatitic (PCA) calcium phosphate material seeded with cells. Preferably, the cells are tissue-forming or tissue-degrading cells. The compositions provided by the present invention are useful for a variety of applications, including in vi ...


5
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Method of preparing a poorly crystalline calcium phosphate and methods of its use. Etex Corporation, Paul T Clark, Clark & Elbing, October 11, 2005: US06953594 (140 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


6
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Methods and products related to the physical conversion of reactive amorphous calcium phosphate. Etex Corporation, Mary Rose Scozzafava, Clark & Elbing, September 12, 2000: US06117456 (135 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


7
Dosuk D Lee, Christian Rey, Maria Aiolova: Bone substitution material and a method of its manufacture. Etex Corporation, Mary Rose Scozzafava, Clark & Elbing, April 10, 2001: US06214368 (126 worldwide citation)

The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provi ...


8
Dosuk D Lee, Christian Rey, Maria Aiolova: Cell seeding of ceramic compositions. Etex Corporation, Brenda Herschbach Jarrell, Sam Pasternack, Choate Hall & Stewart, October 17, 2000: US06132463 (115 worldwide citation)

The present invention provides a synthetic, poorly-crystalline apatitic (PCA) calcium phosphate material seeded with cells. Preferably, the cells are tissue-forming or tissue-degrading cells. The compositions provided by the present invention are useful for a variety of applications, including in vi ...


9
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Orthopedic and dental ceramic implants. Etex Corporation, Clark & Elbing, September 11, 2001: US06287341 (105 worldwide citation)

A method for treating a bone defect is provided by identifying a bone site suitable for receiving an implant; and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant site. A bone defect may be treated by identify ...


10
Dosuk D Lee, Christian Rey, Maria Aiolova: Synthesis of reactive amorphous calcium phosphates. Etex Corporation, Choate Hall & Stewart, November 4, 1997: US05683461 (80 worldwide citation)

The present invention provides a novel process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provi ...