1
Xu Jiangchun, Skeiky Yasir A W, Reed Steven G, Cheever Martin A: Compositions and methods for therapy and diagnosis of prostate cancer. Corixa Corporation, Xu Jiangchun, Skeiky Yasir A W, Reed Steven G, Cheever Martin A, sPOTTER Jane E R, April 12, 2001: WO/2001/025272 (4 worldwide citation)

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise a ...


2
Cheever Martin A, Disis Mary L: Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies. University Of Washington, Cheever Martin A, Disis Mary L, sSHARKEY Richard G, October 3, 1996: WO/1996/030514 (3 worldwide citation)

Compounds and compositions for eliciting or enhancing immune reactivity to HER-2/$i(neu) protein are disclosed. The compounds include polypeptides and nucleic acid molecules encoding such peptides. The compounds may be used for the prevention or treatment of malignancies in which the HER-2/$i(neu) o ...


3
Cheever Martin A, Gheysen Dirk: Her-2/neu fusion proteins. Corixa Corporation, Smithkline Beecham, Cheever Martin A, Gheysen Dirk, PARENT Annette S, August 3, 2000: WO/2000/044899 (3 worldwide citation)

The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and pharmaceutical compositions ($i(e.g.)vaccines) comprising the HER-2/neu fusion proteins and/or nucleic acid mol ...


4
Cheever Martin A, Hand Zimmermann Susan: Compounds and methods for prevention and treatment of her-2/neu associated malignancies. Corixa Corporation, Cheever Martin A, Hand Zimmermann Susan, sPOTTER Jane E R, July 26, 2001: WO/2001/053463 (3 worldwide citation)

Compounds and compositions for eliciting or enhancing immune reactivity to HER-2/neu protein are disclosed. The compounds include antigen-presenting cells, such as dendritic cells, which may be used for the prevention or treatment of malignancies in which the HER-2/neu oncogene is associated.


5
Cheever Martin A, Gheysen Dirk: Her-2/neu fusion proteins. Corixa Corporation, Smithkline Beecham Biologicals, Cheever Martin A, Gheysen Dirk, PARENT Annette S, February 14, 2002: WO/2002/012341 (3 worldwide citation)

The present invention is generally directed to Her-2/neu fusion proteins, nucleic acid molecules encoding Her-2/neu fusion proteins, viral vectors expressing Her-2/neu fusion proteins, and pharmaceutical compositions (e.g., vaccines) comprising the Her-2/neu fusion proteins and/or nucleic acid molec ...


6
Gaiger Alexander, Cheever Martin A, Hand Zimmermann Susan: Methods for diagnosis and therapy of hematological and virus-associated malignancies. Corixa Corporation, Gaiger Alexander, Cheever Martin A, Hand Zimmermann Susan, CHRISTIANSEN William T, February 21, 2002: WO/2002/013847 (3 worldwide citation)

The present invention is directed to methods for detecting and treating hematological and virus-associated malignancies using Her2/neu sequences. The Her2/neu sequences may be polypeptides or polynucleotides.


7
Hand Zimmermann Susan, Cheever Martin A, Foy Teresa M, Lodes Michael J, Kalos Michael D, Mcneill Patricia D, Vedvick Thomas S: Compositions and methods for the therapy and diagnosis of her-2/neu-associated malignancies. Corixa Corporation, Hand Zimmermann Susan, Cheever Martin A, Foy Teresa M, Lodes Michael J, Kalos Michael D, Mcneill Patricia D, Vedvick Thomas S, CHRISTIANSEN William T, February 21, 2002: WO/2002/014503 (3 worldwide citation)

Compositions and methods for the therapy and diagnosis of cancer, particularly Her-2/neu-associated cancers, are disclosed. Illustrative compositions comprise one or more Her-2/neu polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that ...


8
Peace David J, Cheever Martin A: Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy.. Washington Res Found, September 28, 1994: EP0617124-A1

Methods for the detection, monitoring and treatment of malignancies are disclosed. Detection of the proliferation of T cells in response to in vitro exposure to a protein expression product of an activated oncogene or cancer-related gene associated with a malignancy, or detection of immunocomplexes ...


9
Cheever Martin A, Peace David J: Immunoreactivite envers lexpression doncogenes actives pour le diagnostic et le traitement de tumeurs malignes, Immune reactivity to expressed activated oncogenes for diagnosis and treatment of malignancy. Washington Research Foundation, GOWLING LAFLEUR HENDERSON, August 8, 1991: CA2074720

Methods for the detection, monitoring and treatment of malignancies are disclosed. Detection of the proliferation of Tcells in response to in vitro exposure to a protein expression product of an acivated oncogene or cancer-related gene associatedwith a malignancy, or detection of immunocomplexes for ...


10
Disis Mary L, Cheever Martin A: Domaine intracellulaire de la proteine her-2/neu pour la prevention ou le traitement de tumeurs malignes, Intracellular domain of the her-2/neu protein for prevention or treatment of malignancies. University Of Washington, University Of Washington, GOWLING LAFLEUR HENDERSON, October 3, 1996: CA2216601

Compounds and compositions for eliciting or enhancing immune reactivity to HER-2/neu protein are disclosed. The compounds include polypeptides and nucleic acid molecules encoding such peptides. The compounds may be used for the prevention or treatment of malignancies in which the HER-2/neu oncogene ...