1
Charles H Hsiao: Sustained release propranolol tablet. Key Pharmaceuticals, Wegner & Bretschneider, December 3, 1985: US04556678 (42 worldwide citation)

A method of providing a patient suffering from cardiac arrhythmia with a sustained dosage of propranolol over a prolonged period of time comprises orally administering to the patient a tablet consisting essentially of a therapeutically effective amount of propranolol to provide a sustained release t ...


2
Charles H Hsiao: Aspirin tablet. Key Pharmaceuticals, Wegner & Bretschneider, November 26, 1985: US04555399 (41 worldwide citation)

A tablet, which readily disintegrates in gastric fluid to give aspirin crystals coated with a polymeric film preventing the aspirin crystals from contacting the stomach wall but not preventing access of gastric fluid to the aspirin contained within the polymer film, which consists of a plurality of ...


3
Charles H Hsiao, John S Kent: Controlled release naproxen and naproxen sodium tablets. Syntex, Ellen J Wise, Tom M Moran, Alan M Krubiner, February 7, 1989: US04803079 (41 worldwide citation)

A controlled release tablet for once-daily oral administration of about 500-1200 mg of naproxen or naproxen sodium, said tablet comprising a homogeneous matrix comprising about 4-9 weight percent of hydroxypropyl methylcellulose having a number average molecular weight in the range of from about 80, ...


4
Charles H Hsiao, John S Kent: Controlled release naproxen and naproxen sodium tablets. Syntex, Ellen J Buckles, Tom M Moran, Alan M Krubiner, February 18, 1986: US04571333 (39 worldwide citation)

A controlled release tablet for once-daily oral administration of about 500-1200 mg of naproxen or naproxen sodium, said tablet being a homogeneous matrix comprising about 4-9 weight percent of hydroxypropylmethylcellulose having a number average molecular weight in the range of from about 80,000 to ...


5
Charles H Hsiao: Sustained release quinidine dosage form. Key Pharmaceuticals, Warrick E Lee Jr, January 6, 1987: US04634587 (29 worldwide citation)

A sustained release quindine dosage form is made from a plurality of pellets. Each pellet includes a quinidine-containing coating over a nonpareil seed, with a further coating of about 5 to about 15% by weight of a mixture of about 1.5 to about 9 parts by weight ethylcellulose to about 1 part by wei ...


6
Charles H Hsiao: Minipellets. Key Pharmaceuticals, Anita W Magatti, James R Nelson, Stephen I Miller, November 24, 1987: US04708867 (23 worldwide citation)

A minipellet dosage form of prednisone or prednisolone, resistant to attack by saliva but readily dissolvable in gastric juice, which comprises a mixture of prednisone or prednisolone and polyvinylpyrrolidone coated onto a nonpareil seed, and further coated with a layer of dimethylaminoethyl and met ...


7
Charles H Hsiao: Sustained release aspirin. Key Pharmaceuticals, Wegner & Bretschneider, April 2, 1985: US04508702 (11 worldwide citation)

A sustained release aspirin dosage form permits the continuous delivery of aspirin into the gastrointestinal tract for a period of at least eight hours. The sustained release aspirin dosage form comprises a plurality of polymerically coated aspirin crystals each of which comprises an aspirin seed. T ...