1
Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfeffere, Lothar Eggeling, Hermann Sahm, Miroslav Patek: L-lysine-producing corynebacteria and process for the preparation of l-lysine. Degussa Huls Aktiengesellschaft, Pillsbury Madison & Sutro, March 13, 2001: US06200785 (21 worldwide citation)

The invention relates to L-lysine-producing strains of corynebacteria with amplified lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dih ...


2
Caroline Kreutzer, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek: L-lysine-producing corynebacteria and process for the preparation of lysine. Degussa, Pillsbury Winthrop, March 1, 2005: US06861246 (13 worldwide citation)

The invention relates to L-lysine-producing strains of corynebacteria with enhanced pyc gene (pyruvate carboxylase gene), in which strains additional genes, chosen from the group consisting of the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the lysE gene (ly ...


3
Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek: L-lysine-producing corynebacteria and process for the preparation of L-lysine. Dégussa Hüls Aktiengesellschaft, Forschungszentrum Jülich, Pillsbury Winthrop, June 8, 2004: US06746855 (13 worldwide citation)

The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihy ...


4
Brigitte Bathe, Caroline Kreutzer, Bettina Mockel, Georg Thierbach: Coryneform bacteria which produce chemical compounds I. Degussa, Pillsbury Winthrop Shaw Pittman, January 9, 2007: US07160711 (9 worldwide citation)

The invention relates to coryneform bacteria which have, in addition to at least one copy, present at the natural site (locus), of an open reading frame (ORF), gene or allele which codes for the synthesis of a protein or an RNA, in each case a second, optionally third or fourth copy of this open rea ...


5
Brigitte Bathe, Caroline Kreutzer, Stephan Hans: Alleles of the aceA gene from coryneform bacteria. Degussa, Michael A Sanzo, Fitch Even Tabin & Flannery, August 1, 2006: US07083942 (2 worldwide citation)

The invention relates to alleles of the aceA gene from coryneform bacteria coding for isocitrate lyases and processes for the fermentative production of L-lysine using bacteria that contain these alleles.


6
Caroline Kreutzer, Stephan Hans, Mechthild Rieping, Bettina Möckel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm, Miroslav Patek: L-Lysine-producing corynebacteria and process for the preparation of L-lysine. Degussa, Pilsbury Winthrop Shaw Pittman, August 22, 2006: US07094584 (2 worldwide citation)

The invention relates to L-lysine-producing strains of corynebacteria with enhanced lysE gene (lysine export carrier gene), in which strains additional genes chosen from the group comprising the dapA gene (dihydrodipicolinate synthase gene), the lysC gene (aspartate kinase gene), the dapB gene (dihy ...


7
Brigitte Bathe, Caroline Kreutzer, Monika Martens, Mike Farwick, Thomas Hermann, Walter Pfefferle: Methods for producing amino acids in coryneform bacteria using an enhanced sigD gene. Degussa, Smith Gambrell & Russell, May 10, 2005: US06890744 (2 worldwide citation)

The invention relates to an isolated polynucleotide from Corynebacterium glutamicum having a polynucleotide sequence which codes for the sigD gene, and a host-vector system having a coryneform host bacterium in which the sigD gene is present in enhanced form and a vector which carries at least the s ...


8
Bettina Moeckel, Caroline Kreutzer, Brigitte Bathe: Nucleotide sequences coding for the luxR gene. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, April 5, 2005: US06875586 (2 worldwide citation)

The present invention relates to polynucleotides corresponding to the luxR gene and which encode a LuxR transcriptional activator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LuxR transcriptional activation activity. The invention als ...


9
Bettina Moeckel, Caroline Kreutzer: Nucleotide sequences which code for the lysR3 gene. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, November 2, 2004: US06812006 (2 worldwide citation)

The present invention relates to polynucleotides corresponding to the lysR3 gene and which encode a LysR3 transcriptional regulator, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having LysR3 transcriptional regulator activity.


10
Bettina Moeckel, Mike Farwick, Thomas Hermann, Caroline Kreutzer, Walter Pfefferle: Nucleotide sequences for encoding of the lysR2-gene. Degussa, Oblon Spivak McClelland Maier & Neustadt P C, July 18, 2006: US07078502 (2 worldwide citation)

Isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes ...