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Kesteleyn Bart Rudolf Romanie, Raboisson Pierre Jean Marie, Van de, Vreken Wim, Canard Maxime Francis Jean Marie Ghislain: 1, 5, 6-substituted-2-oxo-3-cyano-1, 6a-diaza-tetrahydro-fluoranthenes as anti-infective agents. Tibotec Pharmaceuticals, Kesteleyn Bart Rudolf Romanie, Raboisson Pierre Jean Marie, Van de, Vreken Wim, Canard Maxime Francis Jean Marie Ghislain, WANTE Dirk, July 13, 2006: WO/2006/072636 (1 worldwide citation)

HIV inhibitory compounds of formula: (I) salts and stereoiso mers thereof, wherein R1 and R2 are hydrogen or optionally substituted C1-10alkyl; R3 is: (a) n is 1, 2 or 3; R3a is nitro, cyano, amino, halo, hydroxy, C1-4alkyloxy, hydroxycarbonyl, aminocarbonyl, C1-4alkyloxycarbonyl, mono- or di(C1-4al ...


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Kesteleyn Bart Rudolf Romanie, Van de Vreken Wim, Kindermans Natalie Maria Francisca, Canard Maxime Francis Jean Marie Ghislain, Hertogs Kurt, Bettens Eva, de Vroey Veronique Corine Paul, Jochmans Dirk Edward Desire, Wigerinck Piet Tom Bert Paul, Tahri Abdellah, Wang Jing, Surleraux Dominique Louis Nestor Ghislain: Substituted indolepyridinium as anti-infective compounds. Tibotec Pharmaceuticals, August 26, 2005: KR1020057007708

The present invention concerns the compounds of formula (1) (R3)n P(I) N O R1 R2 their N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites, wherein n is 1, 2 or 3; R 1 is H, CN, halo, aminoC(=O), C(=O)OH, C1-4-alkyloxyC(=O), C1-4alkylC(=O), mono- or di(C1-4alkyl ...


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Kesteleyn Bart Rudolf Romanie, Van de Vreken Wim, Kindermans Natalie Maria Francisca, Canard Maxime Francis Jean Marie Ghislain, Hertogs Kurt, Bettens Eva, de Vroey Veronique Corine Paul, Jochmans Dirk Edward Desire, Wigerinck Piet Tom Bert Paul, Wang Jing, Tahri Abdellah, Surleraux Dominique Louis Nestor Ghislain: Combinations of substituted 1-phenyl-1,5-dihydro-pyrido- [3,2-b] indol-2- ones and other hiv inhibitors. Tibotec Pharmaceuticals, January 24, 2007: KR1020067025921

The present invention concerns combinations comprising a compound of formula (I); the N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters or metabolites thereof, wherein n is 1, 2 or 3; R1 is H, CN, halo, aminoC(=O), C(=O)OH, C1-4alkyloxyC(=O), C1-4 alkylC(=O), mono- or di(C1-4 ...


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