1
Cheuk K Lau, Cameron Black, Michel Belley: N-benzyl-3-indoleacetic acids as antiinflammatory drugs. Merck Frosst Canada, Curtis C Panzer, David L Rose, April 23, 1996: US05510368 (143 worldwide citation)

The invention encompasses the novel compound of Formula I as well as a method of treating inflammation and, in particular, cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. # ...


2
Cheuk Kun Lau, Cameron Black, Daniel Guay, Jacques Yves Gauthier, Yves LeBlanc, Patrick Roy, Yves Ducharme, Pierre Hamel: N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors. Merck Frosst Canada, Curtis C Panzer, David L Rose, June 17, 1997: US05639780 (140 worldwide citation)

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.


3
Cheuk K Lau, Cameron Black, Daniel Guay, Jacques Y Gauthier, Yves LeBlanc, Patrick Roy, Yves Ducharme, Pierre Hamel: N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors. Merck Frosst Canada, Curtis C Panzer, David L Rose, February 18, 1997: US05604253 (136 worldwide citation)

The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention also encomp ...


4
Cameron Black, Joseph A Mancini, Cheuk K Lau, Petpiboon Prasit, Philip J Vickers: 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents. Merck Frosst Canada, Curtis C Panzer, David L Rose, July 25, 1995: US05436265 (131 worldwide citation)

Compounds of the structures shown below are specific inhibitors of cyclooxygenase-2 useful in the treatment of cyclooxygenase-2 mediated disease states such as inflammation, pain and fever, and are non-ulcerogenic. ##STR1##


5
W Cameron Black, Chun Sing Li, Daniel Guay, Petpiboon Prasit, Patrick Roy: Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase. Merck Frosst Canada, Curtis C Panzer, David L Rose, April 25, 1995: US05409944 (113 worldwide citation)

Disclosed are compounds of Formula I useful in the treatment of cyclooxygenase mediated diseases such as pain, fever and inflammation of a variety of conditions including rheumatic fever, symptoms associated with influenza or other viral infections, common cold, low back and neck pain, dysmenorrhea, ...


6
Cameron Black, Ross A Schmidt, Sean M Brockway, Robert M Craig, Todd Partington: System and method for data management. Kroll Ontrack, Merchant & Gould P C, September 5, 2006: US07103602 (44 worldwide citation)

An automated data management system and method for logging, processing, and reporting a large volume of data having different file types, stored on different media, and/or run by different operating systems, includes a first server processor for restoring a plurality of received data files, the data ...


7
Cameron Black, Mario Girard, Daniel Guay, Zhaoyin Wang: Diphenyl stilbenes as prodrugs to COX-2 inhibitors. Merck Frosst Canada, Richard C Billups, David L Rose, March 31, 1998: US05733909 (34 worldwide citation)

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.


8
Cameron Black, Serge Leger, Petpiboon Prasit, Zhaoyin Wang, Pierre Hamel, Yongxin Han, Gregory Hughes: 3,4-diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to COX-2 inhibitors. Merck Frosst Canada, Curtis C Panzer, David L Rose, December 16, 1997: US05698584 (30 worldwide citation)

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.


9
Michel Belley, Jacques Yves Gauthier, Erich Grimm, Yves LeBlanc, Chun Sing Li, Michel Therien, Cameron Black, Petpiboon Prasit, Cheuk Kun Lau, Patrick Roy: (Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors. Merck Frosst Canada, Richard C Billups, David L Rose, February 1, 2000: US06020343 (25 worldwide citation)

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.


10
Cameron Black, Erich Grimm, Serge Leger, Greg Hughes, Petpiboon Prasit, Zhaoyin Wang: Alkylated styrenes as prodrugs to COX-2 inhibitors. Merck Frosst Canada, Richard C Billups, David L Rose, Curtis C Panzer, August 4, 1998: US05789413 (25 worldwide citation)

The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.