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Bichon Daniel, Bussat Philippe, Schneider Michel: Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography.. Sint, November 27, 1991: EP0458745-A1 (292 worldwide citation)

Air or gas filled microballoons bounded by an interfacially deposited polymer membrane which can be dispersed in aqueous carrier liquids to be injected into living organisms or administered orally, rectally and urethrally for therapeutic or diagnostic purposes (echography). The properties of the pol ...


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Schneider Michel, Bussat Philippe, Yan Feng, Guillot Christian: Ultrasound contrast agents and process for the preparation thereof. Bracco International, Schneider Michel, Bussat Philippe, Yan Feng, Guillot Christian, RAVIZZA Claudio, August 19, 2004: WO/2004/069284 (24 worldwide citation)

Method for preparing a lyophilized matrix and, upon reconstitution of the same, a respective injectable contrast agent comprising a liquid aqueous suspension of gas-filled microbubbles stabilized predominantly by a phospholipid. The method comprises preparing an emulsion from an aqueous medium, a ph ...


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Bussat Philippe, Cherkaoui Samir, Fan Hong, Lamy Bernard, Nanjappan Palaniappa, Pillai Radhakrishna K, Pochon Sibylle, Song Bo, Swenson Rolf E: Targeting vector-phospholipid conjugates. Bracco International, Bussat Philippe, Cherkaoui Samir, Fan Hong, Lamy Bernard, Nanjappan Palaniappa, Pillai Radhakrishna K, Pochon Sibylle, Song Bo, Swenson Rolf E, RHOADS Doanld L, June 14, 2007: WO/2007/067979 (16 worldwide citation)

Peptide vectors having high KLDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic m ...


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BUSSAT PHILIPPE, CHERKAOUI SAMIR, FAN HONG HELEN, LAMY BERNARD, NANJAPPAN PALANIAPPA, PILLAI RADHAKRISHNA K, POCHON SIBYLLE, SONG BO, SWENSON ROLF E: Targeting Vector-Phospholipid Conjugates, Zielender Vektor-Phospholipid Konjugaten, Conjugués vecteur de ciblage-phospholipide. BRACCO SUISSE, August 24, 2011: EP2359864-A2 (5 worldwide citation)

Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic me ...


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Bussat Philippe, Cherkaoui Samir, Fan Hong Helen, Lamy Bernard, Nanjappan Palaniappa, Pillai Radhakrishna K, Pochon Sibylle, Song Bo, Swenson Rolf E: Targeting vector-phospholipid conjugates. Bracco Int, September 10, 2008: EP1966388-A2 (5 worldwide citation)

Peptide vectors having high KLDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic m ...