1
Burton H Sage, Robert I Connelly: Low-profile automatic injection device with self-emptying reservoir. Becton Dickinson and Company, Donna R Fugit Ph D, September 28, 1999: US05957895 (251 worldwide citation)

A device for delivering a liquid theraputic preparation into the body of a patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing ...


2
Burton H Sage, Carl Randolph Bock: Method and device for abrading skin. Becton Dickinson and Company, Eric M Lee, Robert E West, December 28, 2004: US06835184 (208 worldwide citation)

A device includes a plurality of microneedles for abrading the stratum corneum of the skin to form a plurality of grooves in the tissue having a controlled depth and width. The microneedles have a length of about 5-250 microns and generally about 5-200 microns. The device is rubbed over the skin to ...


3
Hai Ping Wu, Burton H Sage Jr, Robert F Adrion: Apparatus and method for the detection and classification of articles using flow cytometry techniques. Becton Dickinson and Company, Richard J Rodrick, April 28, 1987: US04661913 (184 worldwide citation)

This invention concerns a flow apparatus and method for the detection of particles in a sample. Particles are moved, substantially one at a time, in a fluid flow stream. An incident beam of illumination is provided so as to be directed at the particles in the flow stream. Data associated with each m ...


4
Burton H Sage, Robert I Connelly: Low-profile automatic injection device with self-emptying reservoir. Becton Dickinson and Company, Donna R Fugit, June 13, 2000: US06074369 (131 worldwide citation)

A device for delivering a liquid therapeutic preparation into the body of a patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing ...


5
Kenneth G Powell, Larry A Monahan, Burton H Sage Jr: Method and apparatus for manufacturing a device. Becton Dickinson and Company, Robert E West, May 30, 2006: US07052268 (125 worldwide citation)

A device, preferably a micro-device, is molded from a plastic material by injection molding, compression molding or embossing. A microabrader can be molded having microneedles for abrading the stratum corneum of the skin to form an abraded site in the tissue for enhancing drug delivery. The micro-de ...


6
Burton H Sage, Robert F Adrion, Michael W Malpass: Optical features of flow cytometry apparatus. Becton Dickinson and Company, Richard J Rodrick, April 28, 1987: US04660971 (115 worldwide citation)

A flow cytometry apparatus includes a transparent liquid flow chamber and a nozzle for providing a stream of particles, to be analyzed, through the flow chamber. A light source is provided along with a lens for focusing the light from the source at a region within the flow chamber through which the ...


7
Burton H Sage Jr: Compensating drug delivery system. Therafuse, Foley & Lardner, June 24, 2003: US06582393 (88 worldwide citation)

A compensating drug delivery system for delivery of medicaments to animals is described. A drug-containing reservoir is connected to a needle array through a flow tube. Medicament delivery to the animal through this flow tube is regulated by the combined action of a metering means and a valving mean ...


8
John L Haynes, Burton H Sage Jr: Iontophresis system having features for reducing skin irritation. Becton Dickinson and Company, Hoffmann & Baron, September 21, 1993: US05246418 (74 worldwide citation)

An iontophoresis drug delivery system includes a device which is attachable to the skin of an animal and having a drug reservoir, an electrolyte reservoir, and electrodes electrically communicating with the reservoirs and with the skin of the animal. An electronic circuit for controlling the rate or ...


9
Burton H Sage Jr, John R DeNuzzio, C Randolph Bock, John L Haynes, Vilambi Reddy: Low cost electrodes for an iontophoretic device. Vyteris, Kirkpatrick & Lockhart, June 24, 2003: US06584349 (67 worldwide citation)

The present invention claims an apparatus for transdermal delivery of medicaments, with novel electrode systems, which avoids burns caused by changes in pH or excessive current applied at the sight of delivery, which is low in cost and easy to manufacture. In the present invention, preferably, the a ...


10
Kenneth G Powell, Larry A Monahan, Burton H Sage Jr: Process of making a molded device. Becton Dickinson and Company, Allen W Wark Esq, December 18, 2001: US06331266 (63 worldwide citation)

A device, preferably a micro-device, is molded from a plastic material by injection molding, compression molding or embossing. A microabrader can be molded having microneedles for abrading the stratum corneum of the skin to form an abraded site in the tissue for enhancing drug delivery. The micro-de ...