1
Schmidt Gunter Dr, Brandes Arndt Dr, Angerbauer Rolf Dr, Loegers Michael Dr, Mueller Gliemann Matthias Dr, Schmeck Carsten Dr, Bremm Klaus Dieter Dr, Bischoff Hilmar Dr, Schmidt Delf Dr, Schuhmacher Joachim Dr, Giera Henry Dr, Paulsen Holger Dr, Naab Paul Dr, Conrad Michael Dr, Stoltefuss Juergen: Cycloalkano-pyridine as cetp inhibitors. Bayer, January 14, 1998: EP0818448-A1 (95 worldwide citation)

Cycloalkano-pyridine compounds of formula (I) and their salts and N-oxides are new. A = 6-10C aryl (optionally up to penta-substituted by halo, NO2, OH, CF3, OCF3, 1-7C alkyl, 1-7C acyl, 1-7C hydroxyalkyl, 1-7C alkoxy or NR3R4); R3, R4 = H, phenyl or 1-6C alkyl; D = 6-10C aryl (optionally substitute ...


2
Schmeck Carsten Dr, Mueller Gliemann Matthias Dr, Schmidt Gunther Dr, Brandes Arndt Dr, Angerbauer Rolf Dr, Loegers Michael Dr, Bremm Klaus Dieter Dr, Bischoff Hilmar Dr, Schmidt Delf Dr, Schuhmacher Joachim Dr: Heterocyclic condensed pyridines as cetp inhibitors. Bayer, January 14, 1998: EP0818197-A1 (86 worldwide citation)

Condensed pyridine derivatives of formula (I), and their salts and N-oxides, are new. A = 6-10C aryl (optionally mono- to penta-substituted by halo, OH, CF3, OCF3, NO2, 1-7C alkyl, acyl, hydroxyalkyl or alkoxy, or NR3R4; D = XR5or C(R6)(R7)R8; R5, R6 = 3-8C cycloalkyl, 6-10C aryl, or 5-7 membered he ...


3
Stolle Andreas Dr, Haebich Dieter Dr, Bartel Stephan Dr, Riedl Bernd Dr, Ruppelt Martin Dr, Wild Hanno Dr, Endermann Rainer Dr, Bremm Klaus Dieter Dr, Kroll Hein Peter Dr, Labischinski Harald Prof Dr, Schaller Klaus Dr, Werling Hans Otto Dr: Heterobenzocyclopentane oxazolidinones having antibacterial activity. Bayer, October 23, 1996: EP0738726-A1 (63 worldwide citation)

2-Oxazolidinone derivs. of formula (I) and their tautomers, isomers and salts are new. R1 = N3, OH, OR2, OSO2R3 or NR4R5; R2 = 1-8C acyl or a protecting gp.; R3 = 1-4C alkyl or phenyl opt. substd. by 1-4C alkyl; R4 = H, 3-6C cycloalkyl, phenyl, 1-8C alkyl, 1-8C alkoxy or protecting gp.; R5 = as for ...


4
Petersen Uwe Dr, Krebs Andreas Dr, Schenke Thomas Dr, Philipps Thomas Dr, Grohe Klaus Dr, Bremm Klaus Dieter Dr, Endermann Rainer Dr, Metzger Karl Georg Dr, Haller Ingo Dr: Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents.. Bayer, July 14, 1993: EP0550903-A1 (46 worldwide citation)

Quinolone- and naphthyridone-carboxylic acid derivatives of the formula (I) in which B is a radical of the formulae in which Y is O or CH2 and R is C2-C5-oxoalkyl, CH2-CO-C6H5, CH2CH2CO2R', , -CH=CH-CO2R' or CH2CH2-CN, in which R' is hydrogen or C1-C3-alkyl, R is H, C1-C3-alkyl, 5-methyl-2-oxo-1,3-d ...


5
Riedl Bernd Dr, Haebich Dieter Dr, Stolle Andreas Dr, Wild Hanno Dr, Endermann Rainer Dr, Bremm Klaus Dieter Dr, Kroll Hein Peter Dr, Labischinski Harald Prof Dr, Schaller Klaus Dr, Werling Hans Otto Dr: 6-membered n-heteroaryloxazolidinones. Bayer, January 31, 1996: EP0694543-A1 (41 worldwide citation)

Nitrogen-contg. heteroaryl-oxazolidinones of formula (I) and their salts and N-oxides are new. R = N3, OH, OR2, OSO2R or NRR; R = 1-8C acyl or OH protecting gp.; R = 1-4C alkyl or phenyl opt. substd. by 1-4C alkyl; R, R = H, 3-6C cycloalkyl, phenyl, 1-8C alkyl or NH2 protecting gp.; or R or R = COR; ...


6
Riedl Bernd Dr, Haebich Dieter Dr, Stolle Andreas Dr, Wild Hanno Dr, Endermann Rainer Dr, Bremm Klaus Dieter Dr, Kroll Hein Peter Dr, Labischinski Harald Prof Dr, Schaller Klaus Dr, Werling Hans Otto Dr: Oxazolidinones substituted by 5-membered heteroaryl group as antibacterial medicine. Bayer, January 24, 1996: EP0693491-A1 (40 worldwide citation)

3-Heteroaryl-2-oxazolidinone derivs. of formula (I) and their salts and S-oxides are new: R1 = azido, OH, OR2, OSO2R3 or NR4R5; R2 = 1-8C acyl or a protecting gp.; R3 = 1-4C alkyl, phenyl or (1-4C alkyl)phenyl; R4, R5 = H, 1-8C alkyl, 3-6C cycloalkyl, phenyl or amino protecting gp., or one of R4, R5 ...


7
Riedl Bernd Dr, Haebich Dieter Dr, Stolle Andreas Dr, Wild Hanno Dr, Endermann Rainer Dr, Bremm Klaus Dieter Dr, Kroll Hein Peter Dr, Labischinski Harald Prof Dr, Schaller Klaus Dr, Werling Hans Otto Dr: Benzofuranyl- and benzothienyloxazolidinones. Bayer, January 31, 1996: EP0694544-A1 (19 worldwide citation)

3-Heteroaryl-2-oxazolidinone derivs. of formula (I) and their salts and S-oxides are new: R1 = azido, OH, OR2, OSO2R3 or NR4R5; R2 = linear or branched 1-8C acyl or a protecting gp.; R3 = e.g. 1-4C alkyl; R4,R5 = e.g. H; A = O or S; D, E, G, L and M = e.g. (a) COOH, halo, CN, SH, CHO, etc., or NR7R8 ...


8
Himmler Thomas Dr, Petersen Uwe Dr, Bremm Klaus Dieter Dr, Endermann Rainer Dr, Stegemann Michael Dr, Wetzstein Heinz Georg Dr: 5-vinyl- and 5-ethinyl-quinolinone- and -naphthyridone-carboxylic acids.. Bayer, September 13, 1995: EP0671391-A1 (17 worldwide citation)

Quinolone and naphthyridone derivs. of formula (I), and their hydrates, acid addn. salts, and alkali-, alkaline earth, silver and guanidinium salts, are new. R1 = 1-4C alkyl (opt. substd. by OH, halo or 1-3C alkoxy), 3-6C cycloalkyl (opt. substd. by halo or 1-3C alkyl), 2-4C alkenyl, 1-3C alkoxy, am ...


9
Petersen Uwe Dr, Krebs Andreas Dr, Schenke Thomas Dr, Kunisch Franz Dr, Philipps Thomas Dr, Grohe Klaus Dr, Bremm Klaus Dieter Dr, Endermann Rainer Dr, Metzger Karl Georg, Haller Ingo Dr, Zeiler Hans Joachim Dr: 7-isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives.. Bayer, December 30, 1992: EP0520240-A1 (17 worldwide citation)

The invention relates to novel quinolone- and -naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation, and to antibacterial agents and feed additives containing them.


10
Petersen Uwe Dr, Krebs Andreas Dr, Schenke Thomas Dr, Grohe Klaus Dr, Bremm Klaus Dieter Dr, Endermann Rainer Dr, Metzger Karl Georg Dr, Zeiler Hans Joachim Dr: 7-azaisoindolinyl-quinolone- and naphthyridoncarboxylic acid derivatives.. Bayer, December 30, 1992: EP0520277-A2 (13 worldwide citation)

Die Erfindung betrifft neue Chinolon- und Naphthyridoncarbonsäure-Derivate, die in 7-Stellung durch einen gegebenenfalls partiell hydrierten Azaisoindolinylring substituiert sind, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel und Futterzusatzstoffe.