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Tanamachi Dawn M, Brams Peter, Black Amelia: Transgenic animals expressing chimeric antibodies for use in preparing human antibodies. Medarex, Tanamachi Dawn M, Brams Peter, Black Amelia, GAVIN Kimberley A, October 18, 2007: WO/2007/117410 (50 worldwide citation)

The invention provides transgene constructs for expressing chimeric antibodies, and transgenic non-human host animals carrying such constructs, wherein the chimeric antibodies comprise human variable regions and constant regions of the non-human transgenic host animal. The presence of immunoglobulin ...


2
Min Jing, Wu Yanli, Finn Rory Francis, Thiele Barrett Richard, Laio Wei, Gladue Ronald Paul, Rajpal Arvind, Paradis Timothy Joseph, Brams Peter, Devaux Brigitte, Wu Yi, Toy Kristopher, Leblanc Heidi N, Huang Haichun: Binding molecules to the human ox40 receptor. Medarex, Pfizer, Min Jing, Wu Yanli, Finn Rory Francis, Thiele Barrett Richard, Laio Wei, Gladue Ronald Paul, Rajpal Arvind, Paradis Timothy Joseph, Brams Peter, Devaux Brigitte, Wu Yi, Toy Kristopher, Leblanc Heidi N, Huang Haichun, BRADY James W, June 25, 2009: WO/2009/079335 (11 worldwide citation)

The present disclosure provides isolated binding molecules that bind to the human OX40R, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells comtaining the vectors, methods of making the binding molecules, pharmac ...


3
Bender Steven Lee, Casperson Gerald Fries, Hu Lowe Dana Dan, Jiang Xin, Li Gang, North Michael Aidan, Wang Jianying, Wickman Grant, Brams Peter, Huang Haichun, Devaux Brigitte, Chen Haibin, Tanamachi Dawn M, Toy Kristopher, Yang Lan, Sproul Tim W, Yamanaka Mark: Alpha 5 - beta 1 antibodies and their uses. Medarex, Pfizer, Bender Steven Lee, Casperson Gerald Fries, Hu Lowe Dana Dan, Jiang Xin, Li Gang, North Michael Aidan, Wang Jianying, Wickman Grant, Brams Peter, Huang Haichun, Devaux Brigitte, Chen Haibin, Tanamachi Dawn M, Toy Kristopher, Yang Lan, Sproul Tim W, Yamanaka Mark, BRADY James W, August 13, 2009: WO/2009/100110 (5 worldwide citation)

The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin α5β1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells ...


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Rajpal Arvind, Devalaraja Madhav, Toy Kristopher, Yang Lan, Huang Halichun, Zhang Jun Z, Brams Peter, Devaux Brigitte, Passmore David B: Antibodies to il-6 and their uses. Medarex, Pfizer, Rajpal Arvind, Devalaraja Madhav, Toy Kristopher, Yang Lan, Huang Halichun, Zhang Jun Z, Brams Peter, Devaux Brigitte, Passmore David B, Brady James W, December 23, 2009: WO/2009/155180 (4 worldwide citation)

Antibodies and antigen-binding portions thereof that bind to human IL-6 are provided. Also provided are nucleic acids encoding such antibodies and antigen binding portions, methods of making such antibodies and antigen binding portions, compositions comprising such antibodies or antigen binding port ...


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Kuhne Michelle, Brams Peter, Tanamachi Dawn M, Korman Alan, Cardarelli Josephine M: Human antibodies that bind cxcr4 and uses thereof. Medarex, Kuhne Michelle, Brams Peter, Tanamachi Dawn M, Korman Alan, Cardarelli Josephine M, DECONTI Giulio A, May 22, 2008: WO/2008/060367 (3 worldwide citation)

The present disclosure provides isolated monoclonal antibodies that specifically bind to CXCR4 with high affinity, particularly human monoclonal antibodies. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of ...


6
Brams Peter, Lichtinger Peter: Apparatus for centering the moulds for injection moulding machines. Krauss Maffei, November 20, 1996: EP0743156-A2 (2 worldwide citation)

A device for correcting axial misalignment of tools on an injection moulding machine, with both fixed and moving tool-carrying platens, includes centering rings on each tool half which engage with a centering ring in the corresponding platen. One of the centering rings (10) comprises an outer (10a) ...


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Wang Yan, Greenberg Robert, Presta Leonard, Pachter Jonathan A, Hailey Judith, Brams Peter, Williams Denise, Srinivasan Mohan, Feingersh Diane: Neutralizing human anti-igfr antibody. Schering Corporation, Wang Yan, Greenberg Robert, Presta Leonard, Pachter Jonathan A, Hailey Judith, Brams Peter, Williams Denise, Srinivasan Mohan, Feingersh Diane, TRIOLO Thomas A, December 4, 2003: WO/2003/100008 (2 worldwide citation)

The present invention includes fully human, neutralizing, monoclonal antibodies against human Insulin-like Growth Factor Receptor-I (IGFR1). The antibodies are useful for treating or preventing cancer in a subject. Also included are methods of using and producing the antibodies of the invention.


9
Meixner Franz Ing, Brams Peter Ing Grad, Schultheis Sven Dr Ing: Apparatus for feeding injection moulding and extrusion moulding units.. Krauss Maffei, February 12, 1992: EP0470510-A2 (1 worldwide citation)

In the case of an apparatus for feeding injection-moulding and extruder units, in order to achieve transporting of the material from the conveying screw 5 to the metering screw 2, or into the prechamber of plunger injection-moulding machines, continuously and unhindered as far as possible, it is pro ...


10
Brams Peter Ing Grad, Schultheis Sven M Dr Ing: Method and apparatus for assembling injection moulded parts.. Krauss Maffei, November 10, 1993: EP0568732-A1 (1 worldwide citation)

In the case of elastomer or silicone seals produced independently of one another by injection moulding, on the one hand, and parts to be sealed having a corresponding sealing groove, on the other hand, the manual insertion of the seal into the sealing groove is complicated and time-consuming because ...