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Kempf Dale J, Plattner Jacob J, Norbeck Daniel W, Baker William R, Fung Anthony K L, Boyd Steven A, Erickson John W, Crowley Steven R: Retroviral protease inhibitors.. Abbott Lab, November 23, 1989: EP0342541-A2 (159 worldwide citation)

A retroviral protease inhibiting compound of the formula: or a pharmaceutically acceptable salt, prodrug or ester thereof.


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Fung Anthony K L, Plattner Jacob J, Baker William R, Armiger Yoek Lin, Rosenberg Saul H, de Biswanath, Mantei Robert A, Boyd Steven A, Kempf Dale J, Sham Hing Leung, Kleinert Hollis D: Non-peptide renin inhibitors.. Abbott Lab, April 25, 1990: EP0364804-A1 (39 worldwide citation)

A renin inhibiting compound of the formula: wherein A is a substituent; R1 is hydrogen, loweralkyl, substituted loweralkyl or loweralkenyl; X is CH2, CHOH, C(O), O, S, S(O), SO2, NH, N(O) or -P(O)O-; R3 is loweralkyl, loweralkenyl or substituted loweralkyl; and T is mimic of the Leu-Val cleavage sit ...


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Arendsen David L, Bhatia Pramila, Boyd Steven A, Condroski Kevin R, Freeman Jennifer C, Gunawardana Indrani W, Lartey Kraig, Mccarty Catherine M, Mort Nicholas A, Patel Meena V, Staeger Michael A, Stewart Andrew O, Stout David M, Zhu Gui Dong: Cell adhesion-inhibiting antiinflammatory compounds. Abbott Laboratories, STRODE Janelle D, December 14, 2000: WO/2000/075145 (1 worldwide citation)

Compounds having formula (I) are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of formula (I), and methods of inhibiting/treating inflammatory diseases in a mammal.