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Bondi Joseph V: Drug delivery device.. Merck & Co, July 10, 1985: EP0147780-A2 (100 worldwide citation)

Polyvinyl alcohol for use as a film coating, a matrix for monolithic device or as a barrier coating for the preparation of controlled release drug delivery systems.


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Bondi Joseph V, Loper Alice E, Cohen Edward M: Ph-mediated drug delivery system.. Merck & Co, October 15, 1986: EP0197504-A2 (28 worldwide citation)

A transdermal delivery system suitable for administering a weakly acidic or basic drug is described which comprises a substantially impermeable backing member, a drug reservoir comprising the drug, a hydroxylated solvent and a buffering agent, and a membrane selectively permeable to the unionized fo ...


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O Neill Joseph L, Bondi Joseph V: Anti-inflammatory topical gel. Merck & Co, Mahon Frank M, Westlake Jr Harry E, Anderson Jr Rudolph J, August 12, 1975: US3899580 (9 worldwide citation)

Methods and compositions for topical application of an anti-inflammatory agent selected from the group consisting of 2'-(4-pyridyl)-6,16.alpha.-dimethyl-11.beta.,17.alpha.,21-trihydroxypregna -4,6-dieno[3,2-c]-pyrazol-20-one, dexamethasone alcohol, prednisolone alcohol, and hydrocortisone alcohol in ...


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Bondi Joseph V, Loper Alice E, Cohen Edward M: Transdermal system for timolol.. Merck & Co, July 2, 1986: EP0186071-A2 (9 worldwide citation)

A system for administering timolol for an extended period is described. The system comprises a backing member (11) substantially impermeable to the drug, a drug reservoir member (12), consisting essentially of timolol as the drug and carrier therefor, and a rate controlling member (15). By the syste ...


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Harwood Richard J, Bondi Joseph V: A water and drug delivery system for suppository use.. Merck & Co, July 10, 1985: EP0147479-A1 (6 worldwide citation)

A drug delivery system designed to deliver water and drug to the site of administration is composed of a core (1) of an aqueous solubulizing system in a wax housing (2), which melts at body temperature, surrounded by a matrix (3) of drug and water-dispersible excipients. The entire unit may also be ...


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Bondi Joseph V, Tasi Pei Kuo, Middaugh C Russell, Volkin David B, Matuszewska Bozena: Stabilized topical acidic fibroblast growth factor formulation.. Merck & Co, April 28, 1993: EP0539087-A1 (2 worldwide citation)

A sterile aqueous medicinal composition containing acidic fibroblast growth factor combined with an amount of heparin sufficient to stabilize acidic fibroblast growth factor, with said acidic fibroblast growth factor and heparin combined with a sufficient amount of hydroxyethyl cellulose to form a v ...


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Bondi Joseph V, Loper Alice E: Transdermal delivery systems.. Merck & Co, December 6, 1989: EP0344840-A2 (2 worldwide citation)

A transdermal delivery system suitable for the drug (4aR-trans)-3,4,4a,5,6,10b-hexahydro-4-propyl-2H naphth[1,2-b]-1,4-oxazin-9-ol over an extended period of time is described.


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Cohen Edward M, Bondi Joseph V, Loper Alice E: Administration transdermique du timolol, Transdermal system for timolol. Merck &Amp Co, GOUDREAU GAGE DUBUC, September 26, 1989: CA1261267

TITLE OF THE INVENTION TRANSDERMAL SYSTEM FOR TIMOLOL ABSTRACT OF THE INVENTION A method and device for administeringtimolol for an extended period is described. By themethod and device, transdermal application of timololmay be accomplished with substantially no irritationto the skin.


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Bondi Joseph V, Loper Alice E, Cohen Edward M: Systeme dadministration de medicament en fonction du ph, Ph-mediated drug delivery system. Bondi Joseph V, Loper Alice E, Merck & Co, Cohen Edward M, GOUDREAU GAGE DUBUC, August 21, 1990: CA1272954

TITLE OF THE INVENTION pH-MEDIATED DRUG DELIVERY SYSTEM ABSTRACT OF THE INVENTION A method and device for delivering acidic or basic drugs in a controlled delivery system is described.


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