1
Bernhard A Sabel, Andrew Freese, William M Saltzman: Controlled drug delivery system for treatment of neural disorders. Massachusetts Institute of Technology, Kilpatrick & Cody, November 28, 1989: US04883666 (225 worldwide citation)

The present invention is a method and composition for treatment of ischemic, metabolic, congenital, or degenerative disorders of the central or peripheral nervous system. The composition is formed by encapsulation within an implantable biocompatible polymeric device of one or more compounds which ha ...


2
Bernhard A Sabel, Erich Kasten: Process and device for the training of human vision. Novavision, Oblon Spivak McClelland Maier & Neustadt P C, October 15, 2002: US06464356 (72 worldwide citation)

The present invention concerns a process for training the visual system of a human by presenting optical stimuli to said human, said stimuli being presented to a zone within the intact visual field of said human and to a zone outside the intact visual field of said human, the latter zone comprising ...


3
Bernhard A Sabel, Andrew Freese: Extended drug delivery of small, water-soluble molecules. Kilpatrick & Cody, May 19, 1992: US05114719 (62 worldwide citation)

A polymeric device releasing biologically active, water-soluble materials having a molecular weight of less than 1000 in a controlled, continuous and linear manner over an extended period of time. Insoluble polymer matrixes can be defined in any shape, size and drug content. When applied to medical ...


4
Jorg Kreuter, Renad N Alyautdin, Dimitri A Karkevich, Bernhard A Sabel: Drug targeting to the nervous system by nanoparticles. Medinova Medical Consulting, Lahive & Cockfield, September 12, 2000: US06117454 (45 worldwide citation)

A novel method of delivering drugs and diagnostics across the blood-brain barrier or blood-nerve barrier is disclosed. Drugs or diagnostic agents are incorporated into nanoparticles which have been fabricated in conventional ways. These nanoparticles are then coated with additional surfactant and gi ...


5
Bernhard A Sabel, Andrew Freese, William M Saltzman, Matthew J During: Polymeric device for controlled drug delivery to the CNS. Massachusetts Institute of Technology, Arnall Golden & Gregory, February 11, 1997: US05601835 (25 worldwide citation)

Disclosed is a polymeric drug delivery system for delivery of any substance to the central nervous system. The delivery system is preferably implanted in the central nervous system for delivery of the drug directly to the central nervous system. These implantable devices can be used, for example, to ...


6
Bernhard A Sabel: Apparatus and method for stimulating a brain of a person. EBS Technologies, Gerald T Bodner, April 15, 2014: US08700167 (2 worldwide citation)

An apparatus for stimulating a brain (3B) of a person (2) comprising a detector (10) for detecting an induced or a spontaneous physiological signal generated by the brain (3B), a control unit (12) being connected to said detector (10) for comparing the detected physiological signal with a criterion ...


7
Bernhard A Sabel, Tobias Günther, Iris Müller: Apparatus and a method for automatic treatment adjustment after nervous system dysfunction. EBS Technologies, Gerald T Bodner, June 17, 2014: US08756190

The present invention relates to an apparatus for automatic adjustment of a treatment of a target person to be treated based on calculated recovery prediction data for predicting a change of a sensory function of said target person in response to said treatment.


8
Bernhard A Sabel, Ulrike Schroeder: Drug targeting system, method of its preparation and its use. NanoDel Technologies, Pabst Patent Group, April 11, 2006: US07025991

A composition and method of fabrication are presented with which nanoparticles may be used as a tool to deliver drugs to a specific target within or on a mammalian body. Specifically, by using stabilizers other than Dextran 70.000 during the polymerization process, according to the present invention ...


9
Bernhard A Sabel: Method and device for training of a user. Bernhard A Sabel, Clark & Elbing, March 25, 2014: US08678833

A training device for training at least one user comprising a user output interface (3) for presenting at least one training task (t) to said user (2), a user input interface (4) for inputting a response of said user (2) to each presented training task (t), means (5) for detecting a performance (p) ...


10
Bernhard A Sabel, Ulrike Schroeder: Drug targeting system, method of its preparation and its use. Oblon Spivak Mcclelland Maier & Neustadt, March 21, 2002: US20020034474-A1

A composition and method of fabrication are presented with which nanoparticles may be used as a tool to deliver drugs to a specific target within or on a mammalian body Specifically, by using stabilizers other than Dextran 70.000 during the polymerization process, according to the present invention, ...