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MASTERSON STEVEN P , HANNAMAN ANDREW W , BERNARD ROBERT M : [de] VERBESSERTES GERÄT FÜR DIE ELEKTRISCH VERMITTELTE ABGABE VON THERAPEUTIKA, [en] IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS, [fr] APPAREIL AMELIORE POUR UNE ADMINISTRATION ELECTRIQUEMENT MEDIEE DAGENTS THERAPEUTIQUES. ICHOR MEDICAL SYSTEMS  , October 14, 2015: EP2929909-A1 (3 worldwide citation)

[en] Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each ...


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Masterson Steven P, Hannaman Andrew W, Bernard Robert M: Improved apparatus for electrically mediated delivery of therapeutic agents. Ichor Medical Systems, Masterson Steven P, Hannaman Andrew W, Bernard Robert M, WESEMAN James C, September 22, 2005: WO/2005/087311 (2 worldwide citation)

Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each elect ...


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Bernard Robert M, Hannaman Andrew W, Bernard Brady M, Masterson Steven P: Method and apparatus for delivery of therapeutic agents. Ichor Medical Systems, Bernard Robert M, Hannaman Andrew W, Bernard Brady M, Masterson Steven P, WESEMAN James C, October 23, 2003: WO/2003/086534 (1 worldwide citation)

Method and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent (30) through an orifice to the patient, a plurality of penetrating electrodes (56) arranged wit ...


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Bernard Robert M: Electrodes and electrode arrays. Ichor Medical Systems, Bernard Robert M, January 26, 2000: EP0973579-A1

Electrodes and electrode array apparatus and systems for in vivo delivery of electrical waveforms rendering therapeutic benefit to the patient are disclosed.


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Bernard Robert M, Hannaman Andrew W, Bernard Brady M, Masterson Steven P: Method and apparatus for delivery of therapeutic agents. Ichor Medical Systems, January 19, 2005: EP1496986-A1

Method and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent (30) through an orifice to the patient, a plurality of penetrating electrodes (56) arranged wit ...


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Hannaman Andrew W, Bernard Robert M: Electroporation electrodes. Ichor Medical Systems, May 23, 2001: EP1100580-A1

Electrodes, electrode array apparatus (A), and systems improve the therapeutic effects of in vivo delivered electrical waveform by utilizing an arrangement wherein the electrode plates satisfy particular ratios of electrode surface areas to separation distances between the electrode plates (X1, X2).


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Masterson Steven P, Hannaman Andrew W, Bernard Robert M: Improved apparatus for electrically mediated delivery of therapeutic agents. Ichor Medical Systems, December 13, 2006: EP1729848-A1

Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each elect ...


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Bernard Robert M, Hannaman Andrew W, Sfiligoi Silvia: Methods for prolonging cell membrane permeability. Ichor Medical Systems, WESEMAN James C, April 20, 2000: WO/2000/021529

Methods for improving the efficiency of electroporation protocols as well as methods to enhance the permeabilized state, in order to improve the intracellular delivery of therapeutic substances, involve the use of at least one agent which is capable of prolonging the permeability of the cell membran ...


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Bernard Robert M: Electrodes and electrode arrays. Ichor Medical Systems, Bernard Robert M, WESEMAN James C, October 29, 1998: WO/1998/047562

Electrodes and electrode array apparatus and systems for $i(in vivo) delivery of electrical waveforms rendering therapeutic benefit to the patient are disclosed.