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Bentzien Joerg Martin, Takahashi Hidenori: Pyrrolo (2, 3-b) pyridine derivatives useful as tec kinase inhibitors. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Bentzien Joerg Martin, Takahashi Hidenori, MORRIS Michael P, May 24, 2007: WO/2007/058832 (46 worldwide citation)

Disclosed are compounds of formula (I), wherein Q, R1, R2, R3, R4 and R5 are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also discl ...


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Mugge Ingo Andreas, Burke Michael Jason, Ralph Mark Stephen, Thomson David S, Hammach Abdelhakim, Kowalski Jennifer A, Bentzien Joerg Martin: Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Mugge Ingo Andreas, Burke Michael Jason, Ralph Mark Stephen, Thomson David S, Hammach Abdelhakim, Kowalski Jennifer A, Bentzien Joerg Martin, MORRIS Michael P, December 21, 2006: WO/2006/135826 (18 worldwide citation)

Compounds of Formula (IA) and (IB) wherein R¿1?, R¿2?, R¿3?, A, B, C, D, and E are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating diseas ...


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Bentzien Joerg Martin, Cook Brian Nicholas, Takahashi Hidenori: 2-(ih-thieno [3,2-c] pyrazol-3yl)-ih-indole derivatives and related compounds as tec kinase inhibitors for the treatment of inflammations and immunological disorders. Boehringer Ingelheim International, Boehringer Ingelheim Pharma & Co Kg, Bentzien Joerg Martin, Cook Brian Nicholas, Takahashi Hidenori, MORRIS Michael P, July 5, 2007: WO/2007/076228 (2 worldwide citation)

Disclosed are compounds of formula (I): (F) wherein Ri, R2, X and Ar are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed ...


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Bentzien Joerg Martin, Takahashi Hidenori: Pyrrolo (2,3-b) pyridine derivatives useful as tec kinase inhibitors. Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, August 20, 2008: EP1957491-A2

Disclosed are compounds of formula (I), wherein Q, R1, R2, R3, R4 and R5 are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also discl ...


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Bentzien Joerg Martin, Cook Brian Nicholas, Takahashi Hidenori: 2-(ih-thieno [3,2-c] pyrazol-3yl)-ih-indole derivatives and related compounds as tec kinase inhibitors for the treatment of inflammations and immunological disorders. Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, September 17, 2008: EP1968580-A2

Disclosed are compounds of formula (I): (F) wherein Ri, R2, X and Ar are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed ...