1
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Methods and apparatus for thermally-induced renal neuromodulation. Ardian, Perkins Coie, November 10, 2009: US07617005 (355 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


2
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Methods and apparatus for thermally-induced renal neuromodulation. Ardian, Perkins Coie, May 18, 2010: US07717948 (335 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...


3
Denise Demarais, Benjamin J Clark, Nicolas Zadno, Erik Thai, Hanson Gifford III: Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. Ardian, Perkins Coie, November 17, 2009: US07620451 (333 worldwide citation)

Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other c ...


4
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai: Methods and apparatus for intravascularly-induced neuromodulation. Ardian, Perkins Coie, July 13, 2010: US07756583 (284 worldwide citation)

Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation, etc., in target n ...


5
Denise Demarais, Benjamin J Clark, Nicolas Zadno, Erik Thai, Hanson Gifford III: Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. Ardian, Perkins Coie, January 18, 2011: US07873417 (162 worldwide citation)

Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation and other c ...


6
Mark Deem, Denise Demarais, Douglas Sutton, Hanson Gifford III, Howard R Levin, Mark Gelfand, Benjamin J Clark: Methods and apparatus for renal neuromodulation. Ardian, Perkins Coie, March 27, 2012: US08145316 (156 worldwide citation)

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the ...


7
Kurt D Sparks, Jeffrey L Emery, Brent D Seybold, David J Kupiecki, C Danielle Pinson, Allen W Madsen, Michael D Keleher, Sergio Salinas, Benjamin J Clark, Matthew R Selmon: Catheter system for vascular re-entry from a sub-intimal space. LuMend, Courtney Staniford & Gregory, February 28, 2006: US07004173 (142 worldwide citation)

A catheter system and corresponding methods are provided for accessing a blood vessel true lumen from a sub-intimal plane of the vessel. The catheter system includes visualization elements for determining the orientation of the true lumen with respect to the sub-intimal plane at an identified entry ...


8
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, January 8, 2013: US08347891 (141 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


9
Denise Demarais, Hanson Gifford III, Mark Deem, Nicolas Zadno, Benjamin J Clark, Andrew Wu, Kenneth J Michlitsch: Apparatus for performing a non-continuous circumferential treatment of a body lumen. Medtronic Ardian Luxembourg r l, June 4, 2013: US08454594 (115 worldwide citation)

Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first posit ...


10
Denise Demarais, Nicolas Zadno, Benjamin J Clark, Erik Thai, Howard R Levin, Mark Gelfand: Ultrasound apparatuses for thermally-induced renal neuromodulation. Medtronic Ardian Luxembourg r l, September 30, 2014: US08845629 (20 worldwide citation)

Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or ...