1
Yun He, Tao Jiang, Kelli L Kuhen, David Archer Ellis, Baogen Wu, Tom Yao Hsiang Wu, Badry Bursulaya: Oxindoles with anti-HIV activity. IRM, Emily Tongro Wu, Genomics Institute of the Novartis Research Foundation, April 17, 2007: US07205328 (9 worldwide citation)

The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophyl ...


2
Hong Liu, Xiaohui He, Ha Soon Choi, Kunyong Yang, David Woodmansee, Zhicheng Wang, David Archer Ellis, Baogen Wu, Yun He, Truc Ngoc Nguyen: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. IRM, Chihang Amy Smith, Genomics Institute of the Novartis Research Foundation, April 17, 2012: US08158634

The invention provides compounds having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and Y are as defined in the specification; as well as pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or di ...


3
Hong Liu, Xiaohui He, Dean Phillips, Xuefeng Zhu, Kunyong Yang, Thomas Lau, Baogen Wu, Yongping Xie, Truc Ngoc Nguyen, Xing Wang: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. IRM A Delaware Liability Company, Genomics Institute of the Novartis Research Foundation, Chihang Amy Smith, April 30, 2013: US08431607

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


4
Bei Chen, Tao Jiang, Thomas H Marsilje, Pierre Yves Michellys, Truc Ngoc Nguyen, Wei Pei, Baogen Wu, Zhaobo Gao, Yonghui Ge, Chen Huang, Yuncheng Li, Xuefeng Zhu: Compounds and compositions as protein kinase inhibitors. Emily Tongco Wu, Genomics Institute of The Novartis Research Foundation, November 26, 2013: US08592432

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kina ...


5
Tao Jiang, Pierre Yves Michellys, Truc Ngoc Nguyen, Wei Pei, Baogen Wu, Xuefeng Zhu: Compounds and compositions as kinase inhibitors. IRM, Emily Tongco Wu, Genomics Institute of the Movartis Research Foundation, August 27, 2013: US08518931

The invention relates to triazine and pyrimidine derivatives having Formula (1) or (2), and methods for using such compounds. For example, the compounds of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, ...


6
Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM, Emily Tongo Wu, Genomics Institute of the Novartis Research Foundation, February 24, 2009: US07495016

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...


7
Baogen Wu, Yun He, Truc Ngoc Nguyen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui He, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM, Emily Tongco Wu, Genomics Institute of the Novartis Research Foundation, October 13, 2009: US07601742

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...


8
Pingda Ren, Baogen Wu, Guobao Zhang, Yongping Xie, Barun Okram, Victor Nikulin, Xia Wang, Ha Soon Choi: Compounds and compositions as protein kinase inhbitors. IRM, Emily Tongco Wu, Genomics Institute of the Novartis Research Foundation, December 7, 2010: US07846923

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


9
Yun He, David Archer Ellis, Beth Marie Anaclerio, Kelli L Kuhen, Baogen Wu, Tao Jiang: Quinolones with anti-HIV activity. IRM, Morgan Lewis & Bockius, March 28, 2006: US07019141

The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of proph ...


10
Baogen Wu, Yun He, Truc Ngyuen, Kelli L Kuhen, David Archer Ellis, Tao Jiang, Xiaohui Xe, Kunyong Yang, Badry Bursulaya: Pyrrolidones with anti-HIV activity. IRM a Delaware, Townsend And Townsend And Crew, August 12, 2004: US20040157859-A1

The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of p ...