1
Jorgensen Steen Troels, Andersen Jens Toenne, Banke Niels, Nielsen Preben: Eubacterial rna-polymerase mutants with altered product production. Novozymes, wu xiaonan bian xinqin, April 27, 2005: CN02826472 (11 worldwide citation)

The present invention relates to an isolated mutant eubacterium comprising at least one mutation resulting in a substitution of at least one amino acid in the beta-subunit of the RNA-polymerase encoded for by the rpoB-gene providing an altered production of a product of interest when said production ...


2
BERKA RANDY, REY MICHAEL, RAMAIYA PREETHI, ANDERSEN JENS TOENNE, RASMUSSEN MICHAEL DOLBJERG, OLSEN PETER BJARKE, NIELSEN ALLAN KENT, BANKE NIELS: [fr] Expression améliorée de Bacillus YweA, [de] Gesteigerte Bacillus YweA-Expression, [en] Increased bacillus YweA expression. NOVOZYMES, NOVOZYMES, February 23, 2011: EP2287179-A2

[en] A Bacillus host cell having increased expression of a polynucleotide encoding an YweA polypeptide, a method for producing the host cell and methods of using the host cell.


3
Persson Jon Martin, Nielsen Allan Kent, Banke Niels: Mutant cells suitable for recombinant polypeptide production. Novozymes, bianxin qin, October 1, 2008: CN200680022607

A mutated bacterial cell producing at least one heterologous polypeptide of interest, wherein said cell has a reduced expression-level of YugJ (SEQ ID NO: 2) or a homologue thereof when compared with an otherwise isogenic but non-mutated cell; methods for producing said cell, and methods for produci ...


4

5
Joergensen Steen Troels, Banke Niels, Wuempelmann Mogens: Improved methods of producing heterologous proteases. Novozymes, March 28, 2007: EP1766000-A1

The present invention provides improved methods of producing S2A (or S1E) proteases in Gram-positive expression host cells, the method comprising the steps of (a) cultivating in a fed-batch fermentation a Gram-positive cell comprising at least one polynucleotide encoding the heterologous S2A/S1E pro ...


6
Persson Jon Martin, Nielsen Allan Kent, Banke Niels: Mutant cells suitable for recombinant polypeptide production. Novozymes, March 12, 2008: EP1896573-A1

A mutated bacterial cell producing at least one heterologous polypeptide of interest, wherein said cell has a reduced expression-level of YugJ (SEQ ID NO: 2) or a homologue thereof when compared with an otherwise isogenic but non-mutated cell; methods for producing said cell, and methods for produci ...


7
Wuempelmann Mogens, Banke Niels, Michaelsen Soren: Sterilisation of a fermentation medium comprising hydrolysed n-source. Novozymes, April 6, 2005: EP1520011-A2

A method for the production of an enzyme of interest, on an industrial scale, comprising a) fermentation of a microbial strain producing an enzyme of interest in a fermentation medium comprising one or more partially prehydrolysed complex N-source(s), wherein said partially prehydrolysed N-source(s) ...


8
Kaasgaard Svend, Banke Niels, Hansen Kim Uhre: Monopropylene glycol added to fermentation. Novozymes, April 6, 2005: EP1520012-A2

A method for fermenting a microorganism, producing a polypeptide of interest, in a culture medium of at least 50 litres, comprising:adding one or more compounds selected from the group consisting of monopropylene glycol, ethylene glycol, trehalose, xylitol, arabitol, dulcitol, mannitol, erythritol, ...


9
Jorgensen Steen Troels, Andersen Jens Toenne, Banke Niels, Nielsen Preben: Eubacterial rna-polymerase mutants for increasing heterologous gene expression. Novozymes, September 29, 2004: EP1461426-A1

The present invention relates to an isolated mutant eubacterium comprising at least one mutation resulting in a substitution of at least one amino acid in the beta-subunit of the RNA-polymerase encoded for by the rpoB-gene providing an altered production of a product of interest when said production ...


10
Wümpelmann Mogens, Banke Niels, Michaelsen Søren: Sterilization of a fermentation medium comprising hydrolysed n-source. Novozymes, NOVOZYMES, January 8, 2004: WO/2004/003216

A method for the production of an enzyme of interest, on an industrial scale, comprising a) fermentation of a microbial strain producing an enzyme of interest in a fermentation medium comprising one or more partially prehydrolysed complex N-source(s), wherein said partially prehydrolysed N-source(s) ...