1
Todd D Campbell, Aws S Nashef: Method of producing prostheses for replacement of articular cartilage and prostheses so produced. American Hospital Supply Corporation, Bernard Rothwell & Brown, December 9, 1986: US04627853 (343 worldwide citation)

Prostheses useful for articulating cartilage replacement, and which are attached to host bone without the use of cements, are derived from bone. Allogenic or xenogenic bone segments are machined into the desired shape and differentially demineralized. The completely demineralized portion has a spong ...


2
Alain Carpentier, Sophie Carpentier, Aws S Nashef: Implantable biological tissue and process for preparation thereof. American Hospital Supply Corporation, Bernard Rothwell & Brown, March 10, 1987: US04648881 (267 worldwide citation)

A process for the preparation of implantable biological tissue, and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes treatment of tissue with solutions prior to implantation which have been found effective in reducing calcification o ...


3
Aws S Nashef, Todd D Campbell: Bone-grafting material. American Hospital Supply Corporation, Bernard Rothwell & Brown, July 7, 1987: US04678470 (251 worldwide citation)

A bone grafting material is derived from allogenic or xenogenic bone by a process that includes tanning with glutaraldehyde. The bone may be pulverized, used as a large block, or machined into a precise pre-determined shape, depending on the bone defect to be repaired. Glutaraldehyde tanning of bone ...


4
Alain Carpentier, Sophie Carpentier, Aws S Nashef: Implantable biological tissue and process for preparation thereof. American Hospital Supply Corporation, Bernard Rothwell & Brown, March 3, 1987: US04647283 (237 worldwide citation)

A process for the preparation of implantable biological tissue, and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes treatment of tissue with solutions prior to implantation which have been found effective in reducing calcification o ...


5
Aws S Nashef, Ahmed I Ahmed: Surfactant treatment of implantable biological tissue to inhibit calcification. Baxter International, Debra D Condino, June 1, 1993: US05215541 (112 worldwide citation)

A process for the preparation of implantable biological tissue, and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes the treatment of tissue with an effective amount of a surfactant to reduce calcification of the implanted tissue.


6
Aws S Nashef, Ahmed I Ahmed: Surfactant treatment of implantable biological tissue to inhibit calcification. Baxter International, Michael C Schiffer, December 5, 1989: US04885005 (108 worldwide citation)

A process for the preparation of implantable biological tissue, and in particular bioprosthetic heart valves, which are prone to calcification after implantation. The process includes the treatment of tissue with an effective amount of a surfactant to reduce calcification of the implanted tissue.


7
Aws S Nashef: Barrier layer for implantable tendons and ligaments. Baxter International, Bernard Rothwell & Brown, January 16, 1990: US04894063 (107 worldwide citation)

Disclosed is a method of interfacing a ligament substitute within a channel of resected bone with a sleeve of soft biological tissue. The sleeve of tissue has overall external dimension sufficient to extend through at least a portion of the resected bone channel and internal dimensions sufficient to ...


8
Aws S Nashef: Method of using biological tissue to promote even bone growth. American Hospital Supply, Donald L Barbeau, July 8, 1986: US04599084 (107 worldwide citation)

Disclosed is a method of using soft biological tissue to interface between a surgically implanted prosthesis, tendon or ligament, and the surface of resected bone to promote the even remodeling of said resected bone.


9
Aws S Nashef: Calcification mitigation of implantable bioprostheses. Baxter Travenol Laboratories, E Anthony Figg, P Flattery, M Schiffer, June 13, 1989: US04838888 (55 worldwide citation)

A process for treating biological tissue prior to implantation to mitigate the calcification of the tissue following implantation comprises incorporating acetylsalicylic acid into the tissue in an amount effective to reduce calcification of the tissue after it is implanted. In accordance with one em ...


10
Aws S Nashef: Elastomeric polymer incorporation into implantable biological tissue to inhibit calcification. American Hospital Supply Corporation, Bernard Rothwell & Brown, September 13, 1988: US04770665 (42 worldwide citation)

A process for the preparation of implantable biological tissue wherein elastomeric copolymers are incorporated into the tissue in an amount sufficient to increase the durability of the tissue as well as to reduce calcification of the tissue upon implantation. Mitigaton of calcification is retained w ...