1
Chu George H, Armstrong Rosa, Chang Robert: Method for improving implant fixation.. Collagen, April 4, 1990: EP0361896-A2 (49 worldwide citation)

Stress-bearing prostheses for replacement or partial replacement of stress-bearing bone are fixed in place lby bony ingrowth by providing a stress-bearing member having a porous region in combination with an osteogenic factor extract or a purified osteogenic inductive protein, optionally in combinat ...


2
Wallace Donald G, Piez Karl A, Smestad Thomas L, Seyedin Saeid, Mcpherson John M, Armstrong Rosa: Bone repair using collagen.. Collagen, February 12, 1986: EP0171176-A2 (44 worldwide citation)

A composition for repairing bone defects by use of suspensions containing purified atelopeptide, reconstituted, fibrillar skin collagen or bone collagen powder or a mixture thereof is disclosed. The suspensions provide matrices for conductive growth of bone into the defect. The skin collagen may als ...


3
Adams Steven W, Armstrong Rosa, Rosen David: Bone growth factors and inhibitors of bone resorption for promoting bone formation.. Celtrix Pharma, November 25, 1992: EP0514720-A2 (13 worldwide citation)

Bone growth factors are used to stimulate new bone formation when administered with agents that inhibit bone resorption. These therapeutic combinations result in an enhanced rate of bone formation with an increase in bone mass.


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Wallace Donald G, Piez Karl A, Smestad Thomas L, Armstrong Rosa, Seyedin Saeid, Mcpherson John M: Bone repair using collagen.. Collagen, May 29, 1991: EP0429438-A2 (8 worldwide citation)

A composition for repairing bone defects by use of suspensions containing purified atelopeptide, reconstituted fibrillar skin collagen is disclosed. The suspensions provide matrices for conductive growth of bone into the defect. The skin collagen may also be lyophilized and used in the form of mats ...


6
Armstrong Rosa, Ellingsworth Larry, Bentz Hanne: Composition pour le traitement de linflammation, Composition for use in treating inflammation. Celtrix Laboratories, Celtrix Pharmaceuticals, ADE & COMPANY, February 6, 1990: CA1265445 (1 worldwide citation)

-38- A COMPOSITION FOR USEIN TREATING INFLAMMATION Abstract Inflammation, acute and/or chronic, is treatedwith a CIF (TGF-.beta.). The CIF may be administered locallyof systemically, depending upon the indication, and doesnot require coadministration of activator or cofactorfor efficacy.


7
Bentz Hanne, Ellingsworth Larry, Armstrong Rosa: (cif) For treating hematopoietic or lymphopoietic disorders.. Collagen, October 16, 1991: EP0451439-A1

Dysfunction or malfunction of hematopoiesis or lymphopoiesis is treated with a CIF. The CIF may be administered locally or systemically, depending upon the indication, and does not require coadminstration of activator or cofactor for efficacy.


8
Adams Steven W, Armstrong Rosa, Rosen David: Utilisation de facteurs de croissance osseuse et dinhibiteurs de la resorption osseuse dans la stimulation de losteogenese, Bone growth factors and inhibitors of bone resorption for promoting bone formation. Celtrix Pharmaceuticals, BORDEN LADNER GERVAIS, November 12, 1992: CA2102429

Bone growth factors are used to stimulate new bone formation when administered with agents that inhibit bone resorption.These therapeutic combinations result in an enhanced rate of bone formation with an increase in bone mass.


9
Bentz Hanne, Thompson Andrea Y, Armstrong Rosa, Rosen David M: Utilisation dune proteine morphogenetique osseuse en combinaison synergique avec tgf-beta pour reparer les os, Use of a bone morphogenetic protein in synergistic combination with tgf-beta for bone repair. Celtrix Laboratories, Celtrix Pharmaceuticals, BATTISON WILLIAMS DUPUIS, June 11, 1992: CA2071912

Bone morphogenetic proteins (BMPs) work in synergistic combination with TGF-.beta.s to provide compositions with in- creased osteogenic activity. Methods of treating bone defects, inducing bone growth and increasing bone marrow cell productionusing these compositions are also disclosed.


10
Chang Robert, Armstrong Rosa, Chu George H: Methode amelioree de fixation des implants, Method for improving implant fixation. Collagen Corporation, ADE & COMPANY, June 20, 1995: CA1335958

Stress-bearing prostheses for replacement orpartial replacement of stress-bearing bone are fixed inplace by bony ingrowth by providing a stress-bearingmember having a porous region in combination with anosteogenic factor extract or a purified osteogenicinductive protein, optionally in combination wi ...