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Antonio Longo, John R Bittner, Randall L Hacker, Federico Bilotti: Circular stapler for hemorrhoidal surgery. Ethicon Endo Surgery, Matthew S Goodwin, August 15, 2000: US06102271 (643 worldwide citation)

A circular sapling instrument for the removal of hemorrhoids has a stapling end effector having a casing, a hollow staple driver within the casing, an annular blade having an open distal end is located within the staple driver, and a elongated interior drive shaft is reciprocable within the staple d ...


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Federico Bilotti, Michele D Arcangelo, Antonio Longo, Jesse J Kuhns: Surgical stapling instrument. Ethicon Endo Surgery, October 12, 2010: US07810690 (249 worldwide citation)

A surgical stapling instrument including a staple fastening assembly with a curved cartridge device and a curved anvil. The cartridge device has at least one curved open row of staples which are formed by a staple forming face of the anvil (12). The anvil can be moved relatively with respect to the ...


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Antonio Longo, John R Bittner, Randall L Hacker: Method of use of a circular stapler for hemorrhoidal procedure. Ethicon Endo Surgery, Matthew S Goodwin, July 4, 2000: US06083241 (194 worldwide citation)

A method for using a circular stapling instrument for the removal of hemorrhoids is disclosed. The circular stapling instrument has a stapling end effector having a stapling head assembly and an anvil assembly movable from an open position spaced away from the stapling head to a closed position adja ...


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Antonio Longo, John R Bittner, Randall L Hacker: Anoscope for hemorrhoidal surgery. Ethicon Endo Surgery, Matthew S Goodwin, November 7, 2000: US06142933 (130 worldwide citation)

An anoscope adapted for the suturing of hemorrhoids during a hemorrhoid removal procedure is disclosed. The anoscope has a distal conical tip, a channel body extending proximally from the distal conical tip and a flange radiused outwardly from the channel. A slot is formed in the channel body and ru ...


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Franco Buzzetti, Antonio Longo, Maristella Colombo: 2-oxindole compounds which are useful as tyrosine kinase inhibitors. Farmitalia Carlo Erba S r l, Oblon Spivak McClelland Maier & Neustadt, December 20, 1994: US05374652 (47 worldwide citation)

Aryl- and heteroarylethenylene derivatives of formula ##STR1## wherein Y is a mono- or bicyclic ring system chosen from (A), (B), (C), (D), (E), (F) and (G) ##STR2## R is a group of formula R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.2 -C.sub.6 alkanoyl; R.sub.2 is hydrogen, halogen, cyano ...


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Franco Buzzetti, Antonio Longo, Maristella Colombo: Methylen-oxindole derivatives compositions and tyrosine kinase inhibition therewith. Farmitalia Carlo Erba S r l, Oblon Spivak McClelland Maier & Neustadt, April 25, 1995: US05409949 (34 worldwide citation)

The invention provides new methylen-indole derivatives of formula (I) ##STR1## wherein R is a group ##STR2## in which R.sub.4 is hydrogen, hydroxy, C.sub.1 -C.sub.6 alkoxy, C.sub.2 -C.sub.6 alkanoyloxy, carboxy, nitro or NHR.sub.7, wherein R.sub.7 is hydrogen or C.sub.1 -C.sub.6 alkyl;


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Franco Buzzetti, Maria Gabriella Brasca, Antonio Longo, Dario Ballinari: Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors. Pharmacia S p A, Oblon Spivak McClelland Maier & Neustadt P C, November 24, 1998: US05840745 (25 worldwide citation)

Novel hydrosoluble 3-arylidene-2-oxindole derivatives, having tyrosine kinase inhibitor activity, encompassed by general formula (I), wherein m is zero, 1 or 2; A is a bicyclic ring chosen from tetralin, naphthalene, quinoline and indole; R.sup.1 is hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.2 -C.sub ...