1
Andrew G C Frazier, Erik J van der Burg, Michael D Lesh: Method and apparatus for closing a body lumen. Appriva Medical, Knobbe Martens Olson & Bear, May 15, 2001: US06231561 (631 worldwide citation)

Disclosed is a closure catheter, for closing a body cavity such as a vessel, or the left atrial appendage of the heart. The closure catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may thereafter be used to draw the tiss ...


2
Chad C Roue, Andrew G C Frazier, Michael D Lesh, Erik J van der Burg: Method and apparatus for closing intracardiac septal defects. Appriva Medical, Knobbe Martens Olson & Bear, September 18, 2001: US06290674 (532 worldwide citation)

Disclosed is a closure catheter, for closing a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a plurality of tissue anchors, which may be deployed into tissue surrounding the opening, and used to draw the ...


3
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Method and apparatus for patching a tissue opening. Appriva Medical, Knobbe Martens Olson & Bear, July 16, 2002: US06419669 (421 worldwide citation)

Disclosed is a closure catheter, for patching a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a deployable patch and a plurality of tissue anchors, which may be deployed to secure the patch to surrounding ...


4
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Transluminal anastomosis method and apparatus. Appriva Medical, Knobbe Martens Olson & Bear, December 11, 2001: US06328727 (404 worldwide citation)

Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anasto ...


5
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Method and apparatus for closing a subcutaneous tissue opening. Appriva Medical, Knobbe Martens Olson & Bear, August 20, 2002: US06436088 (221 worldwide citation)

Disclosed is a closure catheter, for patching a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a deployable patch and a plurality of tissue anchors, which may be deployed to secure the patch to surrounding ...


6
Andrew G C Frazier, Michael D Lesh, Chad C Roue, Erik J van der Burg: Endoluminal anchor. ev3 Sunnyvale, Knobbe Martens Olson & Bear, June 8, 2004: US06746472 (202 worldwide citation)

Disclosed is an anastomosis catheter, for achieving a tissue to tissue or synthetic graft to tissue attachment. The catheter includes a plurality of deployable tissue anchors, which may be laterally deployed into surrounding tissue. The anchors may be used to achieve end to end or end to side anasto ...


7
Chad C Roue, Andrew G C Frazier, Michael D Lesh, Erik J van der Burg: Method of closing an opening in a wall of the heart. EV3 Sunnyvale, Knobbe Martens Olson & Bear, March 30, 2004: US06712804 (194 worldwide citation)

Disclosed is a closure catheter, for closing a tissue opening such as an atrial septal defect, patent foreman ovale, or the left atrial appendage of the heart. The closure catheter carries a plurality of tissue anchors, which may be deployed into tissue surrounding the opening, and used to draw the ...


8
Erik J van der Burg, Dino De Cicco, Andrew G C Frazier, Alex K Khairkahan, Marc S Kriedler, Michael D Lesh, Chad C Roue: Method and device for left atrial appendage occlusion. ev3 Endovascular, Knobbe Martens Olson & Bear, October 31, 2006: US07128073 (189 worldwide citation)

Disclosed is an occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device includes an occlusion member and may also include a stabilizing member. The stabilizing member inhibits compression of the left atrial appendage, facilitating tissue in-growth onto the oc ...


9
Alexander K Khairkhahan, Andrew G C Frazier, Alan R Klenk, Marc S Kreidler, Stewart M Kume, Darrell H Ogi, Chad C Roue, Erik J van der Burg: Adjustable left atrial appendage implant deployment system. ev3 Endovascular, Knobbe Martens Olson & Bear, December 26, 2006: US07152605 (149 worldwide citation)

Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.


10
Andrew G C Frazier, Alexander K Khairkhahan, Erik J van der Burg, Chad C Roue, Alan R Klenk: Left atrial appendage occlusion device with active expansion. Atritech, Beck & Tysver PLLC, October 6, 2009: US07597704 (145 worldwide citation)

An adjustable occlusion device and methods of deploying the device, comprising an actively expandable anchor for use in customizing the fit in a body lumen such as the left atrial appendage. Some embodiments of the actively expandable anchor include a positive force expander as an adjustable occlusi ...