Andreas Huth, Ralph Schmiechen, Wolfgang Kehr, Dieter Palenschat, Gert Paschelke, Helmut Wachtel: 4-(Polyalkoxyphenyl)-2-pyrrolidones (II). Schering Aktiengesellschaft, Millen & White, May 8, 1979: US04153713 (51 worldwide citation)

4-(Polyalkoxyphenyl)-2-pyrrolidones of the formula ##STR1## wherein R.sub.1 and R.sub.2 are hydrocarbon; R.sub.3 is hydrogen or methoxy;

Andreas Huth, Dieter Seidelmann, Karl Heinz Thierauch, Guido Bold, Paul William Manley, Pascal Furet, Jeanette Marjorie Wood, Jürgen Mestan, Jose Brüggen, Stefano Ferrari, Martin Krüger, Eckhard Ottow, Andreas Menrad, Michael Schirner: Anthranilic acid amides and the use thereof as medicaments. Schering, Novartis, Millen White Zelano & Branigan P C, October 17, 2006: US07122547 (36 worldwide citation)

The invention relates to anthranilic acid amides and the use thereof as medicaments for the treatment of diseases that are triggered by persistent angiogenesis, in addition to intermediate products in the production of anthranilic acid amides.

Claus T Braestrup, Jogen A Christensen, Mogens Engelstoft, Gunter Neef, Ulrich Eder, Ralph Schmiechen, Andreas Huth, Dieter Rahtz, Dieter Seidelmann, Wolfgang Kehr, Dieter Palenschat: Pharmacologically active 3-substituted beta-carbolines. Schering Aktiengesellschaft, Millen & White, March 6, 1984: US04435403 (36 worldwide citation)

3-substituted beta-carbolines of the formula ##STR1## wherein R.sup.C is hydrogen, lower alkyl, alkoxyalkyl of up to 6 C-atoms, cycloalkyl of 3-6 C-atoms, aralkyl of up to 8 C-atoms, or (CH.sub.2).sub.n OR.sup.20

Andreas Huth, Ralph Schmiechen, Wolfgang Kehr, Gert Paschelke, Helmut Wachtel, Herbert H Schneider, Dieter Palenschat: 5-(Substituted phenyl)-oxazolidinones and their sulfur analogs. Schering Aktiengesellschaft, Millen & White, January 29, 1980: US04186129 (31 worldwide citation)

Novel 5-(substituted phenyl)-oxazolidinones and their sulfur analogs of Formula I ##STR1## wherein R.sub.1 is optionally substituted lower alkyl, cycloalkyl or cycloalkylalkyl;


Karl Heinz Altmann, Guido Bold, Pascal Furet, Paul William Manley, Jeanette Marjorie Wood, Stefano Ferrari, Francesco Hofmann, Jürgen Mestan, Andreas Huth, Martin Krüger, Dieter Seidelmann, Andreas Menrad, Martin Haberey, Karl Heinz Thierauch: VEGF receptor tyrosine kinase inhibitors. Novartis, Schering Aktiengesellschaft, Lydia T McNally, George R Dohmann, April 12, 2005: US06878720 (22 worldwide citation)

Described are compunds of formula (I), wherein W is O or S; X is NR8; Y is CR9R10—(CH2)n wherein R9 and R10 are independently of each other hydrogen or lower alkyl, and n is an integer of from and including 0 to and including 3; or Y is SO2; R1 is aryl; R2 is a bicyclic heteroaryl group comprising o ...

Claus T Braestrup, Mogens C Nielsen, Joergen A Christensen, Mogens Engelstoft, Henning Schou, Ulrich Eder, Gunter Neef, Andreas Huth, Dieter Rahtz, Ralph Schmiechen: .beta.-Carbolin-3-carboxylic acid derivatives. Ferrosan, Scherling, Millen & White, February 1, 1983: US04371536 (21 worldwide citation)

A .beta.-carbolin-3-carboxylic acid derivative of the formula ##STR1## has valuable pharmacological properties when administered to patients, e.g. humans as a drug, have been shown to possess interesting tranquilizing activity.


Andreas Huth, Ralph Schmiechen, Dieter Rahtz, Dieter Seidelmann, Claus T Braestrup: Substituted .beta.-carbolines, and use thereof as medicinal agents. Schering Aktiengesellschaft, Millen & White, November 18, 1986: US04623649 (17 worldwide citation)

Novel substituted .beta.-carboline derivatives of Formula I ##STR1## wherein R.sup.3 is an oxadiazolyl residue of the formula ##STR2## wherein R.sup.5 stands for lower alkyl of up to 3 carbon atoms or an ester ##STR3## with R.sup.6 being hydrogen or lower alkyl of up to 3 carbon atoms, R.sup.4 is hy ...

Dieter Rahtz, Andreas Huth, Ralph Schmiechen, Dieter Seidelmann, Wolfgang Kehr, Herbert H Schneider, Claus T Braestrup: Substituted 5H-pyrimido[5,4-b]indoles. Schering Aktiengesellschaft, Millen & White, January 14, 1986: US04564610 (17 worldwide citation)

Substituted 5H-pyrimido[5,4-b]indoles of Formula I ##STR1## wherein R.sup.2 is halogen; the oxadiazolyl group ##STR2## wherein R" is lower alkyl with up to 3 carbon atoms; C.sub.1-5 -alkyl, cycloalkyl, aralkyl, or aryl; OR.sup.I, SO.sub.n R.sup.I with n being 0, 1, or 2, or ##STR3## wherein R.sup.I ...