1
Amarpreet S Sawhney: In situ polymerizable hydrogels. Incept, Patterson Thuente Skaar & Christensen P A, November 16, 2004: US06818018 (495 worldwide citation)

Compositions and methods for forming hydrogels in situ through a combination of physical and chemical crosslinking processes are provided in which physical crosslinking is mediated by one or more natural or synthetic components that stabilize the a hydrogel-forming precursor solutions at a depositio ...


2
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill, Syed F A Hossainy: Gels for encapsulation of biological materials. Board of Regents The University of Texas System, Arnall Golden & Gregory, January 12, 1999: US05858746 (491 worldwide citation)

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particula ...


3
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill: Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers. Board of Regents The University of Texas System, Kilpatrick & Cody, April 25, 1995: US05410016 (484 worldwide citation)

Hydrogels of polymerized and crosslinked macromers comprising hydrophilic oligomers having biodegradable monomeric or oligomeric extensions, which biodegradable extensions are terminated on free ends with end cap monomers or oligomers capable of polymerization and cross linking are described. The hy ...


4
Amarpreet S Sawhney: Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels. Incept, Patterson Thuente Skaar & Christensen P A, August 12, 2003: US06605294 (268 worldwide citation)

Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or a ...


5
Amarpreet S Sawhney, John Spiridigliozzi: Methods and apparatus for intraluminal deposition of hydrogels. Confluent Surgical, Patterson Thuenten Skaar & Christensen P A, April 30, 2002: US06379373 (252 worldwide citation)

Methods and apparatus of forming hydrogel systems in situ are provided using a delivery system configured to deliver two or more fluent prepolymer solutions without premature crosslinking. The delivery system comprises separate first and second lumens coupling first and second inlet ports and first ...


6
Jeffrey A Hubbell, Amarpreet S Sawhney: Biocompatible microcapsules. The Board of Regents The University of Texas System, Lyon & Lyon, January 10, 1995: US05380536 (230 worldwide citation)

Biocompatible microcapsules useful for transplanting foreign material into an animal body, and the method of their production, are described, wherein the microcapsules contain an outermost layer of water soluble non-ionic polymers such as PEO to create resistance to cell adhesion on the surface of t ...


7
Amarpreet S Sawhney: Methods and apparatus for in situ formation of hydrogels. Incept, Nicola A Pisano, Fish & Neave, January 30, 2001: US06179862 (224 worldwide citation)

Methods and apparatus of forming in situ tissue adherent barriers are provided using a sprayer capable of applying two or more viscous crosslinkable components to tissue. The sprayer comprises separate spray nozzles for each of two or more crosslinkable solutions, with each nozzle surrounded by an a ...


8
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Syed F A Hossainy: Gels for encapsulation of biological materials. The Board of Regents the Univeristy of Texas System, Lyon & Lyon, June 25, 1996: US05529914 (221 worldwide citation)

This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materials or biomedical devices, as a "glue" to cause more than one b ...


9
Amarpreet S Sawhney, Patrick K Campbell, David A Melanson: Method and apparatus for in situ formation of hydrogels. Incept, Nicola A Pissano, Fish & Neave, December 26, 2000: US06165201 (194 worldwide citation)

Methods and apparatus of forming in situ tissue adherent barriers are provided using a sprayer capable of applying two or more viscous crosslinkable solutions to tissue. The sprayer comprises separate spray nozzles for each of two or more crosslinkable solutions, wherein each nozzle is either surrou ...


10
Jeffrey A Hubbell, Chandrashekhar P Pathak, Amarpreet S Sawhney, Neil P Desai, Jennifer L Hill West, Syed F A Hossainy: Gels for encapsulation of biological materials. Board of Regents The University of Texas System, Arnall Golden & Gregory, November 12, 1996: US05573934 (193 worldwide citation)

Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particula ...