1
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Bioresorbable ceramic composites. Etex Corporation, Hale and Dorr, December 18, 2001: US06331312 (175 worldwide citation)

A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The poorly crystalline apatitic calcium phosphate is characterized in that, when placed in an intramuscular or subcutaneous site, resorption of a ...


2
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Method of preparing a poorly crystalline calcium phosphate and methods of its use. Etex Corporation, Paul T Clark, Clark & Elbing, October 11, 2005: US06953594 (140 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


3
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Methods and products related to the physical conversion of reactive amorphous calcium phosphate. Etex Corporation, Mary Rose Scozzafava, Clark & Elbing, September 12, 2000: US06117456 (135 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


4
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Orthopedic and dental ceramic implants. Etex Corporation, Clark & Elbing, September 11, 2001: US06287341 (105 worldwide citation)

A method for treating a bone defect is provided by identifying a bone site suitable for receiving an implant; and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant site. A bone defect may be treated by identify ...


5
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Bioceramic compositions. Etex Corporation, Clark & Elbing, Paul T Clark, December 6, 2005: US06972130 (59 worldwide citation)

The present invention provides a synthetic, poorly crystalline apatite (PCA) calcium phosphate containing a biologically active agent and/or cells (preferably tissue-forming or tissue-degrading cells). The compositions provided by the present invention are useful for a variety of in vivo and in vitr ...


6
Aliassghar Tofighi, Christian Rey: Synthesis of calcium phosphates by mechano-chemical process. Etex Corporation, Clark & Elbing, January 15, 2008: US07318841 (34 worldwide citation)

A low crystallinity calcium phosphate powder is prepared by mechanically grinding a calcium phosphate solid under grinding forces local heating sufficient to mechanically alloy the calcium phosphate solid and reduce the crystalline domains of the calcium phosphate solid to less than about 100 nm. Th ...


7
Aliassghar Tofighi, Alfred V Vasconcellos, Katherine Jacobs, Pramod Chakravarthy: Mixing device. Etex Corporation, Clark & Elbing, August 18, 1998: US05795330 (23 worldwide citation)

A mixer for the mixing of a first and a second component, comprising a flexible pouch which contains said first component and which has an inner surface that is non-retaining to the components; means for supplying the second component to the chamber for mixing with the first component; and a neck at ...


8
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Method of preparing a poorly crystalline calcium phosphate and methods of its use. Etex Corporation, Clark & Elbing, April 14, 2009: US07517539 (20 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


9
Dosuk D Lee, Christian Rey, Maria Aiolova, Aliassghar Tofighi: Neutral self-setting calcium phosphate paste. Etex Corporation, Clark & Elbing, December 19, 2006: US07150879 (15 worldwide citation)

The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrat ...


10
Aliassghar Tofighi, Alfred V Vasconcellos, Katherine Jacobs, Pramod Chakravarthy: Mixing device. Etex Corporation, Clark & Elbing, November 9, 1999: US05980482 (7 worldwide citation)

A mixer for the mixing of components, comprising a continuous inner surface that is non-retaining to the components, wherein a first portion of the inner surface opposably contacts a second portion of the inner surface during mixing, and a means for supplying a component to the mixer; a kit includin ...