1
Howard Kaufman, Alex Zelenchuk, Ross Flewelling, Philippe Schmid, Ze ev Hed: Methods of monitoring effects of chemical agents on a sample. MediSpectra, Testa Hurwitz & Thibeault, June 7, 2005: US06902935 (29 worldwide citation)

The invention provides methods and systems for monitoring effects of chemical agents on optical signals produced by samples in response to the chemical agents. Preferred methods comprise application of multiple chemical agents that interact to alter an optical signal from the sample. Methods and sys ...


2
Kevin T Schomacker, Thomas M Meese, Ross F Flewelling, Chunsheng Jiang, Christopher E Griffin, Alex Zelenchuk: Methods and apparatus for processing spectral data for use in tissue characterization. MediSpectra, Goodwin Procter, October 16, 2007: US07282723 (21 worldwide citation)

The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral data from valid spectral data. The i ...


3
Kevin T Schomacker, Alex Zelenchuk, Ross Flewelling, Howard Kaufman: Optimal windows for obtaining optical data for characterization of tissue samples. MediSpectra, Testa Hurwitz & Thibeault, August 23, 2005: US06933154 (18 worldwide citation)

The invention provides methods for determining a characteristic of a tissue sample, such as a state of health, using spectral data and/or images obtained within an optimal period of time following the application of a chemical agent to the tissue sample. The invention provides methods of determining ...


4
Kevin T Schomacker, John A Flanagan, Rolf B Saager, Alex Zelenchuk, Thomas M Meese: Methods and apparatus for calibrating spectral data. Fish & Richardson P C, December 2, 2008: US07459696 (12 worldwide citation)

The invention provides methods for calibrating spectral data acquisition systems. These calibration methods produce spectral data sufficiently accurate for use in tissue classification algorithms. The invention improves the accuracy of spectral-based tissue classification schemes, in part, by proper ...


5
Howard Kaufman, Alex Zelenchuk, Ross Flewelling, Philippe Schmid, Ze aposev Hed: Methods of diagnosing disease. MediSpectra, Testa Hurwitz & Thibeault, November 6, 2003: US20030207250-A1 (2 worldwide citation)

The invention provides methods and systems for diagnosing disease in a sample by monitoring optical signals produced by samples in response to the chemical agents. Preferred methods comprise application of multiple chemical agents that interact to alter an optical signal from the sample. Methods and ...


6
Howard Kaufman, Alex Zelenchuk, Ross Flewelling, Philippe Schmid, Ze aposev Hed: Methods of monitoring effects of chemical agents on a sample. Testa Hurwitz & Thibeault, December 26, 2002: US20020197728-A1 (2 worldwide citation)

The invention provides methods and systems for monitoring effects of chemical agents on optical signals produced by samples in response to the chemical agents. Preferred methods comprise application of multiple chemical agents that interact to alter an optical signal from the sample. Methods and sys ...


7
Howard Kaufman, Alex Zelenchuk, Ross Flewelling, Philippe Schmid, Ze aposev Hed: Methods of diagnosing disease. Testa Hurwitz & Thibeault, January 17, 2002: US20020007122-A1 (1 worldwide citation)

The invention provides methods and systems for diagnosing disease in a sample by monitoring optical signals produced by samples in response to the chemical agents. Preferred methods comprise application of multiple chemical agents that interact to alter an optical signal from the sample. Methods and ...


8
Kevin T Schomacker, Alex Zelenchuk, Ross Flewelling, Howard Kaufman: Optimal windows for obtaining optical data for characterization of tissue samples. Testa Hurwitz & Thibeault, February 5, 2004: US20040023406-A1 (1 worldwide citation)

The invention provides methods for determining a characteristic of a tissue sample, such as a state of health, using spectral data and/or images obtained within an optimal period of time following the application of a chemical agent to the tissue sample. The invention provides methods of determining ...


9
Kevin T Schomacker, Thomas M Meese, Ross F Flewelling, Chunsheng Jiang, Christopher E Griffin, Alex Zelenchuk: Methods and apparatus for processing spectral data for use in tissue characterization. MediSpectra, Testa Hurwitz & Thibeault, January 15, 2004: US20040010375-A1 (1 worldwide citation)

The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral data from valid spectral data. The i ...


10
Howard Kaufman, Alex Zelenchuk, Ross Flewelling, Philippe Schmid, Ze aposev Hed: Methods of monitoring effects of chemical agents on a sample. Testa Hurwitz & Thibeault, September 12, 2002: US20020127735-A1 (1 worldwide citation)

The invention provides methods and systems for monitoring effects of chemical agents on optical signals produced by samples in response to the chemical agents. Preferred methods comprise application of multiple chemical agents that interact to alter an optical signal from the sample. Methods and sys ...