1
Alec D Keith, Wallace C Snipes: Buccal drug dosage form. Zetachron, Vorys Sater Seymour & Pease, August 16, 1988: US04764378 (206 worldwide citation)

Buccal dosage forms for transmucosal administration of drugs comprise a pharmaceutical compound dispersed in an erodible matrix comprising


2
Alec D Keith, Wallace Snipes: Protective skin matrix. Key Pharmaceuticals, Wegner & Bretschneider, January 8, 1985: US04492685 (94 worldwide citation)

A protective skin matrix is provided which is particularly suited for the protection of burned or wounded patients. The matrix may be either cured, applied in sheets, or painted or sprayed directly onto the burned or wounded patient. The protective skin matrix includes polyvinylpyrrolidone, polyviny ...


3
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix containing clonidine. Key Pharmaceuticals, Wegner & Bretschneider, September 29, 1981: US04292303 (70 worldwide citation)

There is disclosed a polymeric diffusion matrix for the sustained release of clonidine by transdermal delivery to a patient wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of clonidine.


4
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix containing a vasodilator. Key Pharmaceuticals, Wegner & Bretschneider, September 22, 1981: US04291015 (57 worldwide citation)

A polymeric diffusion matrix containing a vasodilator is provided comprising from about 2 to about 60% of a polar plasticizer, e.g., glycerol, from about 2 to about 15% of a matrix component, e.g., polyvinylalcohol, from about 2 to about 10% of a water-soluble polymer with hydration sites, e.g., pol ...


5
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix containing phenylephrine. Key Pharmaceuticals, Wegner & Bretschneider, October 13, 1981: US04294820 (42 worldwide citation)

There is disclosed a polymeric diffusion matrix for the sustained release of phenylephrine by transdermal delivery to a patient wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of phenylephrine.


6
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix. Key Pharmaceuticals, Wegner & Bretschneider, September 11, 1984: US04470962 (40 worldwide citation)

A polymeric diffusion matrix is provided comprising from about 2 to about 60% glycerol, from about 2 to about 15% polyvinylalcohol, from about 2 to about 10% water soluble polymer with hydration sites which in combination with the remaining ingredients yields a matrix capable of sustained release of ...


7
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix. Key Pharmaceuticals, Wegner & Bretschneider, August 21, 1984: US04466953 (40 worldwide citation)

A polymeric diffusion matrix is provided comprising from about 2 to about 60% glycerol, from about 2 to about 15% polyvinylalcohol, from about 2 to about 10% water soluble polymer with hydration sites which in combination with the remaining ingredients yields a matrix capable of sustained release of ...


8
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix containing propranolol. Key Pharmaceuticals, Wegner & Bretschneider, July 17, 1984: US04460562 (39 worldwide citation)

A self-supporting polymeric diffusion matrix provides for the sustained release of propranolol in order to deliver the propranolol to a patient. The matrix comprises from about 1 to about 60% of a polar plasticizer, from about 6 to about 30% by weight polyvinylalcohol, from about 2 to about 30% by w ...


9
Alec D Keith, Wallace Snipes: Polymeric diffusion matrix containing estrogens. Key Pharmaceuticals, Wegner & Bretschneider, March 20, 1984: US04438139 (33 worldwide citation)

A polymeric diffusion matrix for the sustained release, intravaginal administration of an estrogen is provided. The matrix consists of polyvinylalcohol, polyvinylpyrrolidone and a polar plasticizer.


10
Alec D Keith: Chlorhexidine complex. Zetachron, Webb Burden Ziesenheim & Webb, December 25, 1990: US04980150 (32 worldwide citation)

A chlorhexidine complex is prepared by complexing chlorhexidine (a divalent, cationic antiseptic) with an anionic polymer such as algin or carboxymethylcellulose. The complex is insoluble but can be granulated or crushed to a fine powder. In powdered form the complex forms stable aqueous dispersions ...