1
Teruo Miyata, Albert L Rubin, Kurt H Stenzel, Michael W Dunn: Collagen drug delivery device. Cornell Research Foundation, Edward J Mahler, August 14, 1979: US04164559 (171 worldwide citation)

Chemically-modified collagen membrane prepared at physiologic pH and soluble thereat provides a carrier for ophthalmic medication leaving no removable material after drug release.


2
Daniel M Levine, Sanford R Simon, Bruce R Gordon, Thomas S Parker, Stuart D Saal, Albert L Rubin: Reconstituted HDL particles and uses thereof. The Rogosin Institute, Felfe & Lynch, July 7, 1992: US05128318 (52 worldwide citation)

A reconstituted high density lipoprotein containing particle is disclosed. The particle is useful in removing excess lipid soluble material from a subject to which it is administered, as well as in delivery of lipid soluble pharmaceuticals to subjects or patients.


3
Teruo Miyata, Albert L Rubin, Michael W Dunn, Kurt H Stenzel: Collagen soft contact lens. Opticol Corporation, Edward J Mahler, September 23, 1980: US04223984 (49 worldwide citation)

Soft contact lenses are made from solubilized, defatted, transparent, cross-linked collagen, and/or chemically-modified collagen.


4
Teruo Miyata, Kurt H Stenzel, Albert L Rubin: Chemically and enzymatically modified collagen hemostatic agent. Cornell Research Foundation, Edward J Mahler, July 29, 1980: US04215200 (41 worldwide citation)

Polymers of quaternary-structured collagen of minimum length, diameter and periodicity, and containing a relatively high positive electrostatic charge are claimed as hemostatic agents. Specific examples are guanidnated polymers of the type described, esterified polymers, and esterified-guanidinated ...


5
Teruo Miyata, Albert L Rubin, Kurt H Stenzel, Michael W Dunn: Fiber collagen contact lens. Opticol Corporation, Edward J Mahler, May 19, 1981: US04268131 (37 worldwide citation)

Soft contact lenses are made from purified fiber collagen and mixtures of such fiber with purified solubilized collagen.


6
Daniel M Levine, Thomas S Parker, Albert L Rubin: Methods useful in endotoxin prophylaxis and therapy. The Rogosin Institute, Felfe & Lynch, September 6, 1994: US05344822 (33 worldwide citation)

Treatment and prophylaxis of endotoxin caused toxicity is disclosed. This is accomplished by administering a lipid into which the endotoxin of concern is associated, preferably together with a peptide which is not an apolipoprotein. Preferably, the two components are administered in the form of a re ...


7
Teruo Miyata, Albert L Rubin, Kurt H Stenzel: Chemically-modified fiber collagen hemostatic agents. Cornell Research Foundation, Edward J Mahler, June 2, 1981: US04271070 (23 worldwide citation)

Chemically-modified quaternary-structured fiber collagens of minimum molecular length, diameter and periodicity, and containing a relatively high positive electrostatic charge are claimed as hemostatic agents. Specific examples are guanidinated, esterified, and guanidinated-esterified collagen fiber ...


8
Kanti Jain, Albert L Rubin, Shirin Asina, Barry Smith, Kurt Stenzel: Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation. The Rogosin Institute, Fulbright & Jaworski, March 30, 1999: US05888497 (18 worldwide citation)

Implantable beads which contain agarose and optionally collagen, and are coated with agarose have incorporated within cells which produce diffusible biological products. The beads may be used as implants to modulate a recipient's immune response. The beads may also be used in an in vitro context to ...


9
Kanti Jain, Albert L Rubin, Barry H Smith: Preparation of agarose coated, solid agarose-collagen beads containing secretory cells. The Rogosin Institute, Felfe & Lynch, July 1, 1997: US05643569 (9 worldwide citation)

Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid beads are formed from a suspension containing collagen, agarose and secretory cells such as pancreatic is ...


10
Thomas S Parker, Daniel M Levine, Albert L Rubin, Bruce R Gordon, Stuart D Saal: Methods useful in endotoxin based therapy. The Rogosin Institute, Felfe & Lynch, April 9, 1996: US05506218 (8 worldwide citation)

Treatment and prophylaxis of endotoxin caused toxicity is disclosed. This is accomplished by administering phospholipid containing compositions to the subject. The compositions are protein and peptide free, and may contain triglycerides, or other polar or neutral lipids.