1
Roger DiPaolo
Nathan K Weiner, Patrick J Odoy, Eric Schultz, Mark Jones, James T Overbeck, Herman DeWeerd, David A Stura, Albert K Bukys, Tim J Woolaver, Thomas P Regan, David Bradbury, Eric E McKenzie, Roger DiPaolo, Christopher Miles, Joel M Katz, Oleinik Ovod Ksenia: System and method for scanning of probe arrays. Affymetrix, Affymetrix, March 5, 2013: US08391582 (8 worldwide citation)

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical el ...


2
Roger DiPaolo
Nathan K Weiner, Patrick J Odoy, Eric Schultz, Mark Jones, James T Overbeck, Herman DeWeerd, David A Stura, Albert K Bukys, Tim J Woolaver, Thomas P Regan, David Bradbury, Eric E McKenzie, Roger DiPaolo, Christopher Miles, Joel M Katz, Ksenia Oleinik Ovod: System, method, and product for scanning of biological materials. Affymetrix, Thomas J Siepmann, June 26, 2012: US08208710 (1 worldwide citation)

An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical el ...


3
Brian P Stokes, Pierre Brosens, Stephen O Dea, Albert K Bukys, Steven M Burgarella, Jean I Montagu: Variable-capacitance position transducing. General Scanning, Fish & Richardson, March 24, 1992: US05099386 (18 worldwide citation)

A variable-capacitance transducer detects the angular position of a rotatable member. The transducer includes a first capacitance plate having a plurality of electrically conductive capacitance electrodes, a second capacitance plate spaced therefrom, and a dielectric element located between the plat ...


4
Vincent E Bressler, Albert K Bukys, David Stern: System, method, and computer product for correction of feature overlap. Affymetrix a Corporation Organized under the Laws of Delaware, Affymetrix, December 28, 2006: US20060293860-A1

In one embodiment, a method for correcting feature overlap in biological probe array data is described that comprises (a) receiving a first set of data comprising an intensity value for each of a plurality of features associated with a probe array; (b) calculating a crosstalk parameter for the first ...


5
Albert K Bukys, Peter E Joyce, John A Mundaden: System, method, and product for increased signal and reduced noise detection. Affymetrix, Affymetrix, October 27, 2005: US20050238354-A1

A probe array product is described that comprises a substrate that includes a plurality of biological probes disposed thereon, where at least one of the biological probes is enabled to hybridize a target molecule that comprises a detectable label; and a coating disposed upon a first surface of the s ...


6
David R Smith, Albert K Bukys, Simon Cawley, Daniel M Bartell: System, method, and product for analyzing images comprising small feature sizes. Affymetrix, Affymetrix, August 17, 2006: US20060184038-A1

A method of reconstructing a cell using a raw image of a biological probe array is described that comprises (a) assigning an intensity value to a reconstructed cell of a reconstructed image, where each reconstructed cell comprises a plurality of reconstructed pixels; (b) determining a weighted inten ...