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Winston Edward Gutteridge, Alan Thomas Hudson, Victoria Susan Latter, Mary Pudney: Antiprotozoal medicaments. Glaxo Welcome, Nixon & Vanderhye, July 14, 1998: US05780514 (6 worldwide citation)

The present invention relates to pharmaceutical compositions for the treatment and/or prophylaxis of protozoal infections caused by Kinetoplastida, Apicomplexa, Anaerobic protozoa and Microsporidia comprising 2-�4-(4-chlorophenyl)cyclohexyl!-3-hydroxy-1,4-naphthoquinone or a physiologically acceptab ...


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Alan Thomas Hudson: Medicaments for the treatment of toxoplasmosis. Glaxo Wellcome, Nixon & Vanderhye P C, January 5, 1999: US05856362 (5 worldwide citation)

The present invention relates to the use of 2-�4-(4-chlorophenyl)cyclohexyl!-3-hydroxy-1,4-naphthoquinone or a physiologically acceptable salt or other physiologically funtional derivative thereof for the manufacture of a medicament for the treatment and/or prophylaxis of toxoplasmosis in animals, t ...


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David Drysdale Miller, Sadie Vile, Patrick Vivian Richard Shannon, Laddawan Chunchatprasert, Alan Thomas Hudson: Pyrrolo�3,2-b-!-carbazoles and 1H�1!benzothieno �2,3-f! indoles having anti-tumor activity. University College Cardiff Consultants, Nixon & Vanderhye, December 22, 1998: US05852204 (1 worldwide citation)

The present invention relates to heterocyclic compounds which have been found to have anti-tumor activity. More specifically, the invention concerns pyrrolo�3,2-b!carbazoles and 1H-�1! benzothieno �2,3-f! indoles, methods for their preparation, pharmaceutical formulations containing them and their u ...


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David Drysdale Miller, Sadie Vile, Patrick Vivian Richard Shannon, Laddawan Chunchatprasert, Alan Thomas Hudson: Antitumor tetracyclic compounds. University College Cardiff Consultants, Nixon & Vanderhye, January 11, 2000: US06013807 (1 worldwide citation)

The present invention relates to heterocyclic compounds which have been found to have anti-tumour activity. More specifically, the invention concerns pyrrolo[2,3-b]carbazoles and 1H-[1] benzothieno [2,3-f] indoles, methods for their preparation, pharmaceutical formulations containing them and their ...


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Alan Thomas Hudson, Clive Leonard Yeates: Heterocyclic compounds. The Wellcome Foundation, YANG JIUCHANG, March 2, 1994: CN93105698

Compounds of general formula (II) and physiologically acceptable salts thereof are disclosed.


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Alan Thomas Hudson, Anthon Winchester Randall: Process for preparing 1,4-naphthoquinones. The Welcome Foundation, March 15, 1989: KR1019820004647

Naphthoquinones (I)[R=C1-10 alkyl; n=0,1; X=halo were prepd. by hydrolysis of (II). Thus, 6g 2-trans-(4-t-butylcyclohexyl)methyl/-3- chloro-1,4-naphthoquinone in 60ml dimethoxy ethane was refluxed with 6.0g KOH in 60ml H2O to give 2-/trans-(4-tbutylcyclohexyl)methyl/-3- hydroxy-1,4-naphthoquinone.