1
Ravi Janaki Rama Rao, Pulla, Reddy Muddasani, Adibatla Kali, Satya Bhujanga Rao, Benkaiah, Chowdary Nannapaneni: Polymorphic forms of bortezomib and process for their preparation. Natco Pharma, Ravi Janaki Rama Rao, Pulla, Reddy Muddasani, Adibatla Kali, Satya Bhujanga Rao, Benkaiah, Chowdary Nannapaneni, June 26, 2008: WO/2008/075376 (4 worldwide citation)

The present invention relates to two novel and stable polymorphic forms, namely Form I and Form II of bortezomib (1) and processes for the preparation of these forms. Bortezomib is an anti-neoplastic agent used in the treatment of multiple myeloma.


2
Pulla, Reddy Muddasani, Ajit, Yashwant Junnarkar, Rajasekhara Reddy Peddi, Adibatla Kali, Satya Bhujanga Rao, Madireddi Umamaheshwar Rao Naidu, Venkaiah, Chowdary Nannapaneni: 3-aryloxy 3-substituted propanamines. Natco Pharma, Pulla, Reddy Muddasani, Ajit, Yashwant Junnarkar, Rajasekhara Reddy Peddi, Adibatla Kali, Satya Bhujanga Rao, Madireddi Umamaheshwar Rao Naidu, Venkaiah, Chowdary Nannapaneni, July 10, 2008: WO/2008/081477 (4 worldwide citation)

Present invention relates to novel 3-aryloxy 3-substituted propanamines of formula (I), method of preparing the same and to their use in inhibiting serotonin and norepinephrine reuptake wherein A is a phenyl which is optionally substituted with up to five substituents; a 1- or 2-naphthyl which is un ...



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