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Eugenio Morsiani, Jacek Rozga, Achilles A Demetriou: System for hepatocyte cell isolation and collection. PacFab, Pretty Schroeder & Poplawski P C, October 19, 1999: US05968356 (31 worldwide citation)

The invention resides in apparatus and methods for isolating and collecting cells from donor tissue for later use in medical procedures. The apparatus includes a sealed enclosure, at least one screening material inside the enclosure, an inlet port configured to conduct a fluid through the screening ...


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Jacek Rozga, Achilles A Demetriou: Implantable catheter and method of use. Cedars Sinai Medical Center, Pretty Schroeder & Poplawski, November 18, 1997: US05688237 (20 worldwide citation)

An implantable catheter comprises a flexible elongated catheter body having an inflatable balloon positioned near its distal end. At least one distal delivery port is located distal of the balloon and at least one proximal delivery port is located proximal of the balloon. The balloon and the distal ...


3
Achilles A Demetriou, Andreas Kamlot, Jacek Rozga: Method for conditioning and cryopreserving cells. Cedars Sinai Medical Center, Pretty Schroeder & Poplawski, October 31, 2000: US06140123 (15 worldwide citation)

A method is provided for preconditioning and cryopreservation of cells harvested from a donor. Cells are suspended in a cell conditioning and cryopreservation medium containing a cryopreservative such as Dimethyl Sulfoxide (DMSO) and the suspension is incubated for a period of at least ten minutes a ...


4
Edward F Myers, Albert P Li, Achilles A Demetriou: Artificial liver apparatus and method. Xenogenics, Colleen McKiernan, February 22, 2005: US06858146 (13 worldwide citation)

Artificial liver devices and methods for using the devices to purify a biological fluid are disclosed. The methods include the use of living hepatocytes (23) which are either unattached or attached to inert carriers and suspended in a cell culture medium which circulates in the devices with the hepa ...


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Achilles A Demetriou, Andreas Kamlot, Jacek Rozga: Cell preconditioning and cryopresevation medium. Cedars Sinai Medical Center, Sidley Austin Brown & Wood, November 26, 2002: US06485959 (11 worldwide citation)

Disclosed is a universally-adaptable cell preconditioning and storage medium that can be used for the effective cryopreservation of cells at temperatures less than 4° C. The aqueous medium contains adenosine, a calcium channel blocker, and a nutrient-rich matrix that has a sufficient amount of cell ...


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Eugenio Morsiani, Jacek Rozga, Achilles A Demetriou: Methods for cell isolation and collection. Cedars Sinai Medical Center, Pretty Schroeder & Poplawski, March 30, 1999: US05888409 (8 worldwide citation)

The invention resides in apparatus and methods for isolating and collecting cells from donor tissue for later use in medical procedures. The apparatus includes a sealed enclosure, at least one screening material inside the enclosure, an inlet port configured to conduct a fluid through the screening ...


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Achilles A Demetriou, Julia Y Ljubimova: Method and probe for detection of gene associated with liver neoplastic disease. February 2, 1999: US05866329 (5 worldwide citation)

The present invention provides a gene that encodes proteins associated with liver neoplastic diseases, such as liver cirrhosis and hepatocellular carcinoma. Significantly, these proteins are not expressed in normal, non-neoplastic liver. In accordance with the present invention there also are provid ...


9
Jacek Rozga, Achilles A Demetriou: Artificial gut. Cedars Sinai Medical Center, Pretty Schroeder & Poplawski, November 30, 1999: US05993406 (3 worldwide citation)

An artificial gut (100) comprises a first hollow fiber (203) having an inner surface (215) that is lined with at least a portion of a layer of one or more of a plurality of biological components (205) that typically line a mammalian gut. Further, a second hollow fiber (201) is adjacent the first hol ...


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