1
Aaron V Kaplan: Method and device for treating and enlarging body lumens. Townsend and Townsend Khourie and Crew, August 30, 1994: US05342348 (487 worldwide citation)

The present invention relates generally to stents having delivery matrices which provide for the controlled release of bioactive substances. The delivery matrices comprise porous and erodible filaments, and multiple filaments may be employed in order to release different bioactive substances and/or ...


2
Aaron V Kaplan, James R Kermode, Enrique J Klein: Method and apparatus for sequentially performing multiple intraluminal procedures. Localmed, Townsend and Townsend and Crew, November 5, 1996: US05571086 (288 worldwide citation)

Sleeve catheters having an interactive device near their distal ends are provided for introduction while disposed over conventional interventional and imaging catheters. Exemplary interactive devices on the sleeve catheters include ultrasonic imaging arrays, drug delivery lumens, and the like. The s ...


3
Enrique J Klein, Aaron V Kaplan, Mark Clifford, Martin Overbeek Bloem: Method and apparatus for intraluminal prosthesis delivery. LocalMed, Townsend and Townsend and Crew, July 7, 1998: US05776141 (241 worldwide citation)

A catheter for use in combination with a balloon angioplasty catheter for delivering stents and other intraluminal prostheses comprises a tubular catheter body having a radially expansible portion. The stent is disposed over the radially expansible portion, and structure is provided for retaining th ...


4
Aaron V Kaplan, James R Kermode, Enrique J Klein: Intravascular catheter with infusion array. Localmed, Townsend and Townsend Khourie and Crew, August 9, 1994: US05336178 (234 worldwide citation)

An intravascular catheter provides means for infusing an agent into a treatment site in a body lumen and means for deploying the infusing means adjacent the treatment site which operate independently of one another. In a preferred embodiment, a flexible catheter body has an expansion member attached ...


5
Aaron V Kaplan, James R Kermode, Enrique J Klein: Method and apparatus for sequentially performing multiple intraluminal procedures. Localmed, Townsend and Townsend and Crew, January 5, 1999: US05855563 (204 worldwide citation)

Sleeve catheters having an interactive device near their distal ends are provided for introduction while disposed over conventional interventional and imaging catheters. Exemplary interactive devices on the sleeve catheters include ultrasonic imaging arrays, drug delivery lumens, and the like. The s ...


6
Enrique J Klein, Aaron V Kaplan: Intravascular treatment apparatus and method. LocalMed, Townsend and Townsend Khourie and Crew, January 18, 1994: US05279565 (181 worldwide citation)

An intravascular treatment apparatus provides means for infusing a treatment site with an agent and means for positioning the delivery interface against the treatment site which operate independently of one another. In a preferred embodiment, the apparatus includes a flexible body having a deflectab ...


7
Aaron V Kaplan, Jordan T Bajor, Nubar S Manoukian: Methods and apparatus for pericardial access. Aaron V Kaplan, Cook Alex McFarron Manz Cummings & Mehler, July 23, 2002: US06423051 (130 worldwide citation)

An access tube is used for accessing an anatomic space, such as a pericardial space between the parietal and visceral pericardia. The access tube is advanced against the parietal pericardium and an anchor structure thereon embedded into the parietal pericardium. The access tube can then be used to s ...


8
Aaron V Kaplan, Michael Simons: Localized intravascular delivery of growth factors for promotion of angiogenesis. Localmed, Beth Israel Deaconess Medical Center, Townsend and Townsend and Crew, August 24, 1999: US05941868 (126 worldwide citation)

Angiogenesis in cardiac and other tissues is promoted by the transmural delivery of angiogenic factors such as VEGF, FGF, EGF, and PDGF, through blood vessels and other body lumens into the surrounding tissue. Usually, the angiogenic factor is delivered using a catheter having infusion parts at its ...


9
Aaron V Kaplan, Nubar S Manoukian, Darel E Hodgson, Jordan T Bajor: Apparatus and methods for control of body lumens. Aaron V Kaplan, Townsend and Townsend and Crew, December 19, 2000: US06162238 (114 worldwide citation)

Implantable systems for controlling flow through body lumens comprise a control module and an actuator. The actuator is implanted at least partially over the body lumen to selectively constrict the lumen and control flow therethrough. The control module includes at least a power source for operating ...


10
Aaron V Kaplan, James R Kermode, Enrique J Klein: Intravascular catheter with infusion array. LocalMed, Townsend and Townsend and Crew, March 11, 1997: US05609574 (109 worldwide citation)

An intravascular catheter provides means for infusing an agent into a treatment site in a body lumen and means for deploying the infusing means adjacent the treatment site which operate independently of one another. In a first embodiment, a flexible catheter body has an expansion member attached to ...