1
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, DongFang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin, Scott Kuduk, Christina Harris, Xiu Guo Zhang, Joseph R Bertino: Synthesis of epothilones, intermediates thereto and analogues thereof. Sloan Kettering Institute For Cancer Research, A David Joran, March 20, 2001: US06204388 (48 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilo ...


2
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dang Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Karoline K M Shair, Choate Hall & Stewart, June 5, 2001: US06242469 (41 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


3
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dang Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Karoline K M Shair, Choate Hall & Stewart, April 9, 2002: US06369234 (34 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


4
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, DongFang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto and analogues thereof. Sloan Kettering Institute for Cancer Research, Karoline K M Shair, Choate Hall & Stewart, November 13, 2001: US06316630 (33 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilo ...


5
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dand Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Karoline K M Shair, Choate Hall & Stewart, September 4, 2001: US06284781 (27 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


6
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dang Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Karoline K M Shair, Choate Hall & Stewart, October 9, 2001: US06300355 (23 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


7
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dang Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Brenda H Jarrell, C Hunter Baker, Choate Hall & Stewart, December 2, 2003: US06656961 (11 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


8
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, Dang Fang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin: Synthesis of epothilones, intermediates thereto, analogues and uses thereof. Sloan Kettering Institute for Cancer Research, Brenda H Jarrell, C Hunter Baker, Choate Hall & Stewart, April 20, 2004: US06723854 (10 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions bas ...


9
Samuel J Danishefsky, Peter Bertinato, Dai Shi Su, DongFang Meng, Ting Chao Chou, Ted Kamenecka, Erik J Sorensen, Aaron Balog, Kenneth A Savin, Scott Kuduk, Christina Harris, Xiu Guo Zhang, Joseph R Bertino: Synthesis of epothilones, intermediates thereto and analogues thereof. Sloan Kettering Institute for Cancer Research, Brenda Herschbach Jarrell, C Hunter Baker, Choate Hall & Stewart, August 5, 2003: US06603023 (10 worldwide citation)

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof, useful in the treatment of cancer and cancer which has developed a multidrug-resistant phenotype. Also provided are intermediates useful for preparing said epothilo ...


10
Samuel J Danishefsky, Alexy Rivkin, Fumikiko Yoshimura, Ting Chao Chou, Ana E Gabarda: Synthesis of epothilones, intermediates thereto and analogues thereof. Sloan Kettering Institute for Cancer Research, Brenda Herschbach Jarrell, C Hunter Baker, Choate Hall & Stewart, July 26, 2005: US06921769 (7 worldwide citation)

The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compoun ...