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Av Gay Yossef, Greenberg David: Antimicrobial gas-releasing ear drainage tubes. Enox Biopharma, Av Gay Yossef, Greenberg David, POLONENKO Daniel, March 26, 2009: WO/2009/036571 (10 worldwide citation)

A nitric oxide gas-releasing conduit configured for surgical implantation through a patient's tympanic membrane. The nitric oxide gas-releasing conduit comprises a gas-permeable cured resin material configured for releasably sequestering therein gas. The gas-permeable cured resin material is charged ...


2
Av Gay Yossef, Mahler Livia, Miller Christopher C: Biofilm-inhibiting catheters and tubings. Enox Biopharma, Av Gay Yossef, Mahler Livia, Miller Christopher C, POLONENKO Daniel R, October 15, 2009: WO/2009/124379 (9 worldwide citation)

Antimicrobial and biofilm-inhibiting nitric oxide-releasing medical appliances for installation into a patient, and processes for producing the medical appliances. The medical appliances are configured for conveying materials into and out of the patient's body and may comprise tubings or pouching sy ...


3
AV GAY Yossef, BACH Horacio: FORMULATIONS TOPIQUES CAPTURANT LOXYDE NITRIQUE, NITRIC OXIDE-SEQUESTERING TOPICAL FORMULATIONS. TOPICAL THERAPEUTIC AGENT, AV GAY Yossef, BACH Horacio, G E EHRLICH, November 15, 2012: WO/2012/153331 (3 worldwide citation)

Topical formulations, comprising a carrier having gaseous nitric oxide sequestered therein, and optionally further comprising a pharmaceutically, cosmetic or cosmeceutically active agent, which are useful is medical, cosmetic or cosmeceutic applications, are provided herein. Systems, devices and pro ...


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Aharonowitz Yair, Van Der Voort Lucia Helena Mar, Cohen Gerald, Bovenberg Roelof Ary Lans, Schreiber Rachel, Argaman Anat, Av Gay Yossef, Nan Helena Maria, Kattevilder Alfred, Palissa Harriet, Van Liempt Henk: An oxido reductase enzyme system obtainable from p. chrysogenum, the set of genes encoding the same and the use of oxido reductase enzyme systems or genes encoding the same for increasing antibiotic production.. Gist Brocades, December 27, 1991: EP0462674-A1 (1 worldwide citation)

A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of beta -lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes en ...


6
Newton Gerald L, Av Gay Yossef, Fahey Robert C: Acyl glucosaminyl inositol amidase family and methods of use. Univ California, Univ British Columbia, September 4, 2002: EP1235926-A2

The present invention provides a family of bacterial acyl glucosaminylinositol amidases with amidase activity against S-conjugate amides, particularly mycothiol-derived S-conjugate amides. The invention amidases are characterized by a highly conserved 20 amino acid N-terminal region and four highly ...


7
Arad Dorit, Av Gay Yossef: Antimicrobial compounds against staphylococci, mycobacteria, and other infectious agents. Exegenics, Arad Dorit, Av Gay Yossef, HANSEN Eugenia S, October 23, 2003: WO/2003/087127

Novel antimicrobial compounds effective against mycobacteria, staphylococci, and other infectious agents are disclosed. Representative antimicrobial compounds have the following chemical structure: Wherein: (Formula I), M and L independently can be hydrogen, halogen, -CF3, -OMe (Me=methyl), -OR4 whe ...


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Sareen Dipti, Newton Gerald L, Fahey Robert C, Buchmeier Nancy, Steffek Micah, Av Gay Yossef, Rawat Mamta, Koledin Teresa: Methods of use of the enzymes of mycothiol synthesis. The Regents Of The Univeristy Of California, The University Of British Columbia, Sareen Dipti, Newton Gerald L, Fahey Robert C, Buchmeier Nancy, Steffek Micah, Av Gay Yossef, Rawat Mamta, Koledin Teresa, HAILE Lisa A, October 30, 2003: WO/2003/089585

The present invention utilizes three families of bacterial enzymes, which play a key role in mycothiol biosynthesis. The three families are bacterial cysteine:glucosaminyl inositol ligases (MshC) with catalytic ligase activity for ligation of glucosaminyl inositol and cysteine, bacterial acetyl-CoA: ...


9
Arad Dorit, Av Gay Yossef: Antimicrobial compounds. Exegenics, Arad Dorit, Av Gay Yossef, HANSEN Eugenia S, February 12, 2004: WO/2004/012506

Novel antimicrobial compounds are disclosed. Representative antimicrobial compounds have the following chemical structure. (I)


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Av Gay Yossef, Drews Steven Jeffrey, Cowley Siobhan: Screening for modulators of pkng activity. The University Of British Columbia, Av Gay Yossef, Drews Steven Jeffrey, Cowley Siobhan, ROBINSON Christopher J, September 12, 2003: WO/2003/074728

The present invention relates to a method for identifying compounds capable of affecting the activity of members of a Mycobacterium serine/threonine kinase family. A new method of developing drugs for treating M. tuberculosis is provided. Unique kinases (PknB, PknG, PknH, PknJ) to the organism are u ...



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