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COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS. September 27, 2018: US20180273467-A1

The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA ar ...


2
DETERMINATION OF TGF-BETA PATHWAY ACTIVITY USING UNIQUE COMBINATION OF TARGET GENES. September 27, 2018: US20180271438-A1

A bioinformatics process which provides an improved means to detect TGF-β cellular signaling pathway in a subject, such as a human, based on the expression levels of one or more unique target gene(s) of the TGF-β cellular signaling pathway measured in a sample. The invention includes an apparatus co ...


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COMPOSITIONS COMPRISING A CASEIN AND METHODS OF PRODUCING THE SAME. Perfect Day, September 27, 2018: US20180271111-A1

Disclosed herein are methods and compositions including casein, and methods for making these compositions.


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INCORPORATING ARRAYS OF JOSEPHSON JUNCTIONS IN A JOSEPHSON JUNCTION RING MODULATOR IN A JOSEPHSON PARAMETRIC CONVERTER. September 27, 2018: US20180277733-A1

A Josephson parametric converter is provided. The Josephson parametric converter includes a multi-Josephson junction ring modulator having arrays of Josephson junctions arranged in a ring configuration with nodes inter-dispersed between the arrays. The Josephson parametric converter includes resonat ...


5
September 27, 2018: US20180275129-A1

The present invention provides compositions including reagents for detecting human autoantibodies against at least two proteins selected from the group consisting of ANGTPL4, DKK1, EPHA2, LAMC2, SPON2, SSR2, GAL1, GFRA1, LRRC15, CD147, CD320, CDH3, LRP10, SPINT2, SUSD2, and CST2, and their use in de ...


6
SINGLE-SENSOR HYPERSPECTRAL IMAGING DEVICE. September 27, 2018: US20180275325-A1

The present disclosure generally relates to hyperspectral spectroscopy, and in particular, to systems, methods and devices enabling a single-sensor hyperspectral imaging device. Hyperspectral (also known as “multispectral”) spectroscopy is an imaging technique that integrates multiples images of an ...


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CANISTER APPARATUS AND BASKET FOR TRANSPORTING, STORING AND/OR SUPPORTING SPENT NUCLEAR FUEL. September 27, 2018: US20180277273-A1

A canister apparatus, basket apparatus and combinations thereof for transporting and/or storing high level radioactive waste, such as spent nuclear fuel. In one embodiment, the invention can be a basket apparatus for supporting a plurality of spent nuclear fuel rods within a containment structure, t ...


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USING NEW EDGES FOR ANOMALY DETECTION IN COMPUTER NETWORKS. Los Alamos National Security, September 27, 2018: US20180278641-A1

Creation of new edges in a network may be used as an indication of a potential attack on the network. Historical data of a frequency with which nodes in a network create and receive new edges may be analyzed. Baseline models of behavior among the edges in the network may be established based on the ...


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BALLISTIC RESISTANT THERMOPLASTIC SHEET, PROCESS OF MAKING AND ITS APPLICATIONS. Honeywell International, September 27, 2018: US20180274135-A1

Woven fabrics are formed from high tenacity fibers or tapes that are loosely interwoven with adhesive coated filaments, to composite articles formed therefrom, and to a continuous process for forming the composite articles.


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NON-HUMAN ANIMALS HAVING A HUMANIZED A PROLIFERATION-INDUCING LIGAND GENE. Regeneron Pharmaceuticals, September 27, 2018: US20180271070-A1

Non-human animals, cells, methods and compositions for making and using the same are provided, wherein the non-human animals and cells comprise a humanized a proliferation-inducing ligand gene. Non-human animals and cells that express a human or humanized a proliferation-inducing ligand protein from ...