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John Leicester Williams
John L Williams, Said T Gomaa, Joseph G Wyss: Antero-posterior placement of axis of rotation for a rotating platform. Depuy Products, Paul Maginot, Maginot Moore & Beck, January 21, 2010: US20100016978-A1

A knee replacement system includes a femoral component including a lateral condylar articulating portion and a medial condylar articulating portion, a tibial tray including an upper articulating surface, and a tibial insert including (i) a first articulating portion for articulating with the lateral ...


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John Leicester Williams
Joseph G Wyss, John L Williams, Said T Gomaa: Knee prostheses with enhanced kinematics. Depuy Products, Paul Maginot, Maginot Moore & Beck Chase Tower, January 21, 2010: US20100016979-A1

A knee replacement system includes a proximal tibial posterior camming portion defined by a first radius of curvature with a first origin in a first medio-lateral plane, a distal tibial posterior camming portion defined by a second radius of curvature with a second origin in a second medio-lateral p ...


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Rothberg Jonathan M, Hinz Wolfgang, Johnson Kim L, Bustillo James M, Leamon John H, Schultz Jonathan: Methods and apparatus for measuring analytes using large scale fet arrays. Ion Torrent Systems Incorporated, Rothberg Jonathan M, Hinz Wolfgang, Johnson Kim L, Bustillo James M, Leamon John H, Schultz Jonathan, Trevisan Maria A, January 21, 2010: WO/2010/008480 (96 worldwide citation)

Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time ...


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Honigberg Lee, Verner Erik, Buggy Joseph, Loury David, Chen Wei: Inhibitors of brutons tyrosine kinase for the treatment of solid tumors. Pharmacyclics, Honigberg Lee, Verner Erik, Buggy Joseph, Loury David, Chen Wei, Hostetler Michael J, January 21, 2010: WO/2010/009342 (68 worldwide citation)

Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.


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Haydar Simon N, Bothmann Hendrick, Ghiron Chiara, Maccari Laura, Micco Iolanda, Nencini Arianna, Zanaletti Riccardo: Alpha7 nicotinic acetylcholine receptor inhibitors. Wyeth, Siena Biotech, Haydar Simon N, Bothmann Hendrick, Ghiron Chiara, Maccari Laura, Micco Iolanda, Nencini Arianna, Zanaletti Riccardo, Jarrell Brenda Herschbach, January 21, 2010: WO/2010/009290 (46 worldwide citation)

The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psyc ...


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Neelamkavil Santhosh Francis, Boyle Craig D, Harris Joel M, Stamford Andrew W, Hao Jinsong, Neustadt Bernardt R, Chackalamannil Samuel, Xia Yan, Greenlee William J: Bicyclic heterocycle derivatives and their use as gpcr modulators. Schering Corporation, Neelamkavil Santhosh Francis, Boyle Craig D, Harris Joel M, Stamford Andrew W, Hao Jinsong, Neustadt Bernardt R, Chackalamannil Samuel, Xia Yan, Greenlee William J, Bergman Jeffrey P, January 21, 2010: WO/2010/009207 (45 worldwide citation)

The present invention relates to Bicyclic Heterocycle Derivatives of Formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a diabetic complication, a metabolic disorder, a cardio ...


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Pokhariyal Akhilesh, Ponnekanti Seshaiah: Method and apparatus for setting an uplink transmit power level for a wireless communication unit. Ipaccess, Pokhariyal Akhilesh, Ponnekanti Seshaiah, Wray Antony, January 21, 2010: WO/2010/006909 (44 worldwide citation)

An access point for supporting communication in a femto cell of a cellular communication network. The access point comprises transceiver circuitry arranged to enable communication with one or more wireless communication units located within the femto cell, and signal processing logic arranged to det ...


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Gilliam Ryan J, Albrecht Thomas A, Jalani Nikhil, Knott Nigel Antony, Decker Valentin, Kostowskyj Michael, Boggs Bryan, Farsad Kasra: Low-energy 4-cell electrochemical system with carbon dioxide gas. Calera Corporation, Gilliam Ryan J, Albrecht Thomas A, Jalani Nikhil, Knott Nigel Antony, Decker Valentin, Kostowskyj Michael, Boggs Bryan, Farsad Kasra, Witt Eric, January 21, 2010: WO/2010/008896 (44 worldwide citation)

A low-voltage, low-energy electrochemical system and method of producing hydroxide ions and/or bicarbonate ions and/or carbonate ions utilizing significantly less than the typical 3V used across the conventional anode and cathode to produce the ions; consequently, carbon dioxide emissions attributab ...


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Gilliam Ryan, Albrecht Thomas A, Jalani Nikhil, Knott Nigel Antony, Decker Valentin, Kostowskyj Michael, Boggs Bryan, Gorer Alexander, Farsad Kasra: Co2 utilization in electrochemical systems. Calera Corporation, Gilliam Ryan, Albrecht Thomas A, Jalani Nikhil, Knott Nigel Antony, Decker Valentin, Kostowskyj Michael, Boggs Bryan, Gorer Alexander, Farsad Kasra, Scherer David C, January 21, 2010: WO/2010/009273 (43 worldwide citation)

A low-voltage, low-energy electrochemical system and method of removing protons and/or producing a base solution comprising hydroxide and carbonate/bicarbonate ions, utilizing carbon dioxide in a cathode compartment that is partitioned into a first cathode electrolyte compartment and a second cathod ...