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Patra Michael, Degünther Markus, Layh Michael, Wangler Johannes, Maul Manfred: (De) Beleuchtungsoptik für die projektions-mikrolithografie sowie mess- und überwachungsverfahren für eine derartige beleuchtungsoptik, (En) Illumination lens system for projection microlithography, and measuring and monitoring method for such an illumination lens system. Carl Zeiss Smt, Patra Michael, Degünther Markus, Layh Michael, Wangler Johannes, Maul Manfred, HOFMANN Matthias, May 29, 2008: WO/2008/061681 (74 worldwide citation)

(EN) Disclosed is a microlithographic projection exposure system (1) comprising an illumination system (4) with an illumination lens system (5) for illuminating an illumination field on a reticle level (6). The illumination lens system is equipped with a light distribution device (12a) encompassing ...


12
Link Darren R, Weiner Michael, Marren David, Rothberg Jonathan M: Microfluidic devices. Raindance Technologies, Link Darren R, Weiner Michael, Marren David, Rothberg Jonathan M, ELRIFI Ivor R, May 29, 2008: WO/2008/063227 (65 worldwide citation)

The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel i ...


13
Oda Atsushi, Kobayashi Toshiro, Sato Keiichi, Okabe Hiroko, Kamikawa Susumu, Wada Kozo: Evaporation source and vacuum vapor deposition system using the same. Yamagata Promotional Organization For Industrial Technology, Mitsubishi Heavy, Mitsubishi Hitachi Metals Machinery, May 29, 2008: JP2008-121098 (62 worldwide citation)

PROBLEM TO BE SOLVED: To provide an evaporation source with a nozzle structure where a film thickness distribution is made uniform in the width direction of a substrate, and to provide a vacuum vapor deposition system using the same.SOLUTION: A vapor produced by vaporizing or subliming a vapor depos ...


14
Jain Akash, Mcgrew Robert J, Gettings Nathan: Creating data in a data store using a dynamic ontology. Palantir Technologies, Jain Akash, Mcgrew Robert J, Gettings Nathan, PALERMO Christopher J, May 29, 2008: WO/2008/064207 (59 worldwide citation)

In one embodiment, a method comprises creating and storing an ontology for a data store in response to receiving first user input defining the ontology, wherein the ontology comprises a plurality of data object types and a plurality of object property types; creating one or more parser definitions i ...


15
White Stephen L, Kesicki Edward A, Thorsett Eugene, Ruan Fuqiang, Farouz Francine: Thienopyrimidinones for treatment of inflammatory disorders and cancers. Eli Lilly &, White Stephen L, Kesicki Edward A, Thorsett Eugene, Ruan Fuqiang, Farouz Francine, SMITH Michael G, May 29, 2008: WO/2008/064018 (58 worldwide citation)

The current invention provides compounds of formula (1): wherein: one of Q1, Q2 and Q3 is S, and the other of two of Q1, Q2 and Q3 are -CR1-, which are inhibitors of PI3K-delta. These compounds are useful for treatment of conditions mediated by PI3K-delta, such as hematopoietic cancers, immune disor ...


16
Møller Thorleif: Oligonucleotides for modulating target rna activity. Querdenker Aps, Møller Thorleif, PLOUGMANN Sundkrogsgade 9 Post Box 831 DK 2100 Copenhagen Ø, May 29, 2008: WO/2008/061537 (53 worldwide citation)

The present invention describes oligonucleotides that bind to microRNA target sites in target RNAs, such as mRNAs. The oligonucleotides of the invention may mediate RNase H degradation of the target RNA, mediate RNAi of the target RNA or prevent microRNA regulation of the target RNA. The oligonucleo ...


17
Sitlani Ayesha, Sparrow Carl P, Pandit Shilpa, Condra Jon H, Hammond Holly A: Antagonists of pcsk9. Merck & Co, Sitlani Ayesha, Sparrow Carl P, Pandit Shilpa, Condra Jon H, Hammond Holly A, MERCK 126 East Lincoln Avenue Rahway NJ 07065 0907, May 29, 2008: WO/2008/063382 (53 worldwide citation)

Antagonists of human proprotein convertase subtilisin-kexin type 9 ('PCSK9') are disclosed. The disclosed antagonists are effective in the inhibition of PCSK9 function and, accordingly, present desirable antagonists for the use in the treatment of conditions associated with PCSK9 activity. The prese ...


18
Kawaminami Hiroo: Lighting apparatus, and lighting system. Matsushita Electric Works, May 29, 2008: JP2008-124922 (51 worldwide citation)

PROBLEM TO BE SOLVED: To provide a lighting apparatus and a lighting system in which reduction in optical output of a light source can be suppressed to an irreducibly minimum.SOLUTION: The lighting system includes a lighting apparatus 1 which outputs an optical signal from a light source L, and a re ...


19
Zhuo Jincong, Xu Meizhong, He Chunhong, Zhang Colin, Qian Ding Quan, Burns David M, Li Yunlong, Metcalf Brian, Yao Wenqing: Imidazotriazines and imidazopyrimidines as kinase inhibitors. Incyte Corporation, Zhuo Jincong, Xu Meizhong, He Chunhong, Zhang Colin, Qian Ding Quan, Burns David M, Li Yunlong, Metcalf Brian, Yao Wenqing, GODDARD Christine PhD, May 29, 2008: WO/2008/064157 (49 worldwide citation)

The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.


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Dolle Roland E, Worm Karin, Goodman Allan J, Chu Guo Hua, Lebourdonnec Bertrand: Pyridine compounds and methods of their use. Adolor Corporation, Dolle Roland E, Worm Karin, Goodman Allan J, Chu Guo Hua, Lebourdonnec Bertrand, CHERRY David A, May 29, 2008: WO/2008/063625 (40 worldwide citation)

Novel pyridine compounds, pharmaceutical compositions containing the pyridine compounds, and methods of their pharmaceutical use are disclosed. In certain embodiments, the pyridine compounds are agonists and/or ligands of cannabinoid receptors and may be useful, inter alia, for treating and/or preve ...