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Levy Michael J, Camilleri Michael L, Murray Joseph A, Sandborn William J: Obesity treatment and device. Mayo Foundation For Medical Education And Research, Levy Michael J, Camilleri Michael L, Murray Joseph A, Sandborn William J, BRUESS Steven C, December 22, 2005: WO/2005/120363 (127 worldwide citation)

A method and apparatus are disclosed for treating obesity includes an artificial fistula created between gastrointestinal organs such as between the stomach and the colon. The method includes selecting an implant (10, 10', 10'', 10''', 210', 410', 310', 510', 610) comprising a passageway (20, 20', 2 ...


12
Bartetzko Norbert, Bartetzko Robert, Specht Bernfried: Device and method for analyte measurement. Albatros Technologies & Co Kg, Bartetzko Norbert, Bartetzko Robert, Specht Bernfried, December 22, 2005: WO/2005/121759 (118 worldwide citation)

A method is provided for forming an analyte testing device. The method comprises providing a substrate and forming at least one electrode by screen printing; and covering at least the electrode with a layer containing zwitterionic compound and/or having the zwitterionic compound in a mediator layer ...


13
Hayflick Joel S, Pefaur Noah, Puri Kamal D, Tino William, Kawakami Toshi, Kawakami Yuko: Methods for treating mast cell disorders. Icos Corporation, La Jolla Institute For Allergy And Immunology, Hayflick Joel S, Pefaur Noah, Puri Kamal D, Tino William, Kawakami Toshi, Kawakami Yuko, NEVILLE Katherine L, December 22, 2005: WO/2005/120511 (116 worldwide citation)

The present invention provides methods of inhibiting mast cell activity by administering a selective inhibitor of phosphoinositide 3-kinase delta (P13K&dgr;). The invention also provides methods for treating or preventing a condition associated with undesirable mast cell activity in an individual co ...


14
Freeman Dominique M, Schulte Tom, Cane Michael, Alden Don, Schumann Matt: Method and apparatus for a fluid sampling device. Pelikan Technologies, Freeman Dominique M, Schulte Tom, Cane Michael, Alden Don, Schumann Matt, TUNG Hao Y, December 22, 2005: WO/2005/120365 (100 worldwide citation)

Methods and apparatus are provided for manufacturing an analyte detecting device. In one embodiment, the apparatus comprises a housing; a penetrating member driver; a cartridge containing a plurality of penetrating members; a display on the cartridge; a linear slider on the housing, the slider coupl ...


15
Deshmukh Ajay, Hegener Jason H, Mauze Ganapati, Von, Duering Monika U, Freeman Dominique M: Tissue interface on a fluid sampling device. Pelikan Technologies, Deshmukh Ajay, Hegener Jason H, Mauze Ganapati, Von, Duering Monika U, Freeman Dominique M, TUNG Hao Y, December 22, 2005: WO/2005/120197 (98 worldwide citation)

Methods and apparatus are provided for an analyte detecting device. In one embodiment, the apparatus for assisting fluid sampling comprising a tissue interface having a tissue interface surface. The surface is shaped to provide pressure on the tissue, except at one location. The tissue interface may ...


16
Mauze Ganapati, Lum Paul, Deshmukh Ajay, Marsot Travis, Boecker Dirk, Freeman Dominique M, Alden Don, Cane Michael, Schumann Matt, Ross James: Methods and apparatus for an integrated sample capture and analysis disposable. Pelikan Technologies, Mauze Ganapati, Lum Paul, Deshmukh Ajay, Marsot Travis, Boecker Dirk, Freeman Dominique M, Alden Don, Cane Michael, Schumann Matt, Ross James, TUNG Hao Y, December 22, 2005: WO/2005/120199 (98 worldwide citation)

Methods and apparatus are provided for an analyte detecting device. In one embodiment, the device comprises a cartridge having a plurality of cavities; and a plurality of penetrating members at least partially contained in the cavities of the single cartridge wherein the penetrating members are slid ...


17
Okada Yuko, Egawa Saku, Teramoto Ritsu, Arai Minoru, Koseki Atsushi, Asa Yasuhiro, Tanaka Hirobumi, Kawabe Takuya, Tajima Taiji: Self-travelling cleaner. Hitachi Home &Amp Life Solutions, December 22, 2005: JP2005-352707 (87 worldwide citation)

PROBLEM TO BE SOLVED: To provide a self-travelling cleaner of which travelling is appropriately selected between a regular travelling mode and a random travelling mode depending on the situations of a room to be cleaned.SOLUTION: The self-travelling cleaner that cleans a surface of a floor of the sp ...


18
Oishi Keitaro: Network communication terminal. Matsushita Electric, December 22, 2005: JP2005-354249 (86 worldwide citation)

PROBLEM TO BE SOLVED: To improve the probability of successful reception processing applied to data that are normally acknowledged by relieving a load imposed on re-transmission processing or the like in multicast transmission/reception.SOLUTION: A communication terminal includes management informat ...


19
Bhat Balkrishen, Prakash Thazha P, Dande Prasad, Allerson Charles, Griffey Richard, Swayze Eric E: Double strand compositions comprising differentially modified strands for use in gene modulation. Isis Pharmaceuticals, Bhat Balkrishen, Prakash Thazha P, Dande Prasad, Allerson Charles, Griffey Richard, Swayze Eric E, CALDWELL John, December 22, 2005: WO/2005/121371 (70 worldwide citation)

The present invention provides douse stranded compositions wherein each strand is modified to have a motif defined by positioning of ß-D-ribonucleosides and sugar modified nucleosides. More particularly, the present compositions comprise one strand having a gapped motif and another strand having a g ...


20
Jones Robert M, Semple Graeme, Xiong Yifeng, Shin Young Jun, Ren Albert S, Lehmann Juerg, Fioravanti Beatriz, Bruce Marc A, Choi Jin Sun Karoline: Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto. Arena Pharmaceuticals, Jones Robert M, Semple Graeme, Xiong Yifeng, Shin Young Jun, Ren Albert S, Lehmann Juerg, Fioravanti Beatriz, Bruce Marc A, Choi Jin Sun Karoline, GODDARD Christine A, December 22, 2005: WO/2005/121121 (70 worldwide citation)

The present invention relates to certain substituted aryl and heteroaryl derivative of Formula (I) that are modulators of metabolism, especially of the activity of a GPCR, referred to herein as RUP3. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related dis ...