41
Rothenberg Barry E: Methods for the detection of a mutant receptor diagnostic for hemochromatosis. Rothenberg Barry E, FRENCH Timothy A, December 18, 1997: WO/1997/047655

The invention provides a method for the diagnosis of hemochromatosis or detection of a genetic predisposition for hemochromatosis by detecting the presence of a mutation in the hemochromatosis receptor class I-like heavy chain. The method involves detection of the hemochromatosis receptor using anti ...


42
Gray Patrick W: Chitinase materials and methods. Icos Corporation, RIN LAURES Li Hsien, December 18, 1997: WO/1997/047752

The present invention provides purified and isolated polynucleotide sequences encoding human chitinase. Also provided are materials and methods for the recombinant production of human chitinase products which are expected to be useful as products for treating fungal infections or for development of ...


43
Kumar Rajan: Nuclease protection assays. Sarnoff Corporation, SILVERIO John V, December 18, 1997: WO/1997/047640

The invention provides nuclease protection assay, as illustrated in the Figure, comprising: (A) attaching a nucleic acid probe comprising a first nucleotide sequence to a solid surface area; (B) contacting the nucleic acid probe with a nucleic acid template under conditions that promote hybridizatio ...


44
Tod Timothy William, Allan Richard Douglas: Coin dispensing apparatus. Mars Incorporated, Tod Timothy William, Allan Richard Douglas, MUSKER David Charles, December 18, 1997: WO/1997/047470

A coin dispensing apparatus comprises a coin receiving means (12) adapted to hold a stack S of coins which comprises at least two coins disposed one upon the other and coin engaging means (58) for engaging a circumferential edge portion of an endmost coin (C1) of such a stack. The coin receiving mea ...


45
Kumar Rajan: Padlock probe detection. Sarnoff Corporation, SILVERIO John V, December 18, 1997: WO/1997/047769

The invention relates to the detection of a polynucleotide using a padlock probe, whereby a hybridization process is combined with ligation to irreversibly capture polynucleotides of interest. The invention relates both to the padlock probe itself, as well as to methods of use, which allow for varyi ...


46
Arad Dorit, Elias Yuval, Elhanany Orna, Shokhen Michael, Puzis Leopold: Novel anti-viral compounds. Arad Dorit, Elias Yuval, Elhanany Orna, Shokhen Michael, Puzis Leopold, ANTHONY CASTORINA, December 18, 1997: WO/1997/047270

A compound having formula (I) wherein the substituents are as defined herein. Also provided are pharmaceutical compositions including a compound of formula (I) in a pharmaceutical carrier, for treating a disease caused by a picornavirus. Also provided is a method of treating a subject with a disease ...


47
Wittkötter Erland: Apparatus and method for the protected transmission and representation of electronically published documents. Wittkötter Erland, BEHRMANN Niels, December 18, 1997: WO/1997/048034

Publishing electronic media over electronic marketing channels such as the Internet promises interesting business opportunities; however, due to the possibility of copying digital media in a qualitatively perfect manner, a protection of user rights in such electronic media becomes a key question. To ...


48
Myers Jan Willem Marinus: Gravity infusion set for medical infusions. Filtertek, Myers Jan Willem Marinus, December 18, 1997: WO/1997/047339

A gravity infusion set for medical infusions having a drip chamber which by means of a hollow spike can be connected to a bottle containing the infusion liquid. A flexible line with one end is connected to the drip chamber and includes at its other end a coupling device for the infusion needle. Betw ...


49
Morrish David L: Dispenser package for flat rolled paper products and method of use. Mcguire Martha L, Morrish David L, TYSON Timothy T, December 18, 1997: WO/1997/047444

A portable dispenser package (20) is shown having a friction closing plastic dispenser (24) with a roll (22) of paper inside. To use the dispenser, the consumer opens the dispenser around a hinge (36) and removes a label (56) which protects the roll. The consumer lays the free end (28) of the paper ...


50
Heinzen Richard J, Mccabe Dennis E: Module de conduite dechantillons pour un appareil dacceleration de particules, Sample delivery module for particle acceleration apparatus. Powderject Vaccines, Powderject Vaccines, OGILVY RENAULT SENCRLSRL, December 18, 1997: CA2257141

A sample delivery module for use in conjunction with a particle acceleration apparatus includes a fitting for connecting the sample delivery module to the apparatus. The sample delivery module provides a particle acceleration path which includes a portion adapted to receive a sample of particles coa ...