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David C Yates: Hemostatic surgical cutting or stapling instrument. Ethicon Endo Surgery, April 29, 1997: US05624452 (914 worldwide citation)

A hemostatic surgical instrument is provided for coagulation, cauterization and/or welding of tissue especially in the performance of endoscopic procedures. The instrument compresses the tissue between interfacing surfaces of first and second elements. A preferred application of the invention is in ...


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Nils Lonberg, Robert M Kay: Transgenic non-human animals for producing heterologous antibodies. GenPharm International, Townsend and Townsend and Crew, April 29, 1997: US05625126 (866 worldwide citation)

The invention relates to transgenic non-human animals capable of producing heterologous antibodies and methods for producing human sequence antibodies which bind to human antigens with substantial affinity.


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Ronald J Tuch: Intravascular stent and method. Medtronic, Daniel W Latham, Harold R Patton, April 29, 1997: US05624411 (561 worldwide citation)

A method for making an intravascular stent by applying to the body of a stent a therapeutic substance and then overcoating the therapeutic substance with a porous polymer. The inclusion of a porous polymer in intimate contact with a drug on the stent allows the drug to be retained on the stent durin ...


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Gregory P Winter, Alexander R Duncan, Dennis R Burton: Antibodies with altered effector functions. Scotgen Biopharmaceuticals Incorporated, Spencer & Frank, April 29, 1997: US05624821 (538 worldwide citation)

An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.


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Robin F B Turner, Douglas G Kilburn, Michael R Phelps: Biosensor and interface membrane. The University of British Columbia University Industry Liaison Office, Christensen O Connor Johnson & Kindness PLLC, April 29, 1997: US05624537 (487 worldwide citation)

A regenerable biosensor probe adapted for positioning in a bioreactor comprises a selectively permeable interface membrane, a porous protein-receiving matrix adjacent to the interface membrane, an indicating electrode, an inlet conduit through which fresh protein conjugate may flow to the protein-re ...


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Yoshiyuki Yoneda, Kazuto Tsuji: Semiconductor device in a resin package housed in a frame having high thermal conductivity. Fujitsu, Armstrong Westerman Hattori McLeland & Naughton, April 29, 1997: US05625222 (453 worldwide citation)

A semiconductor device including a substrate, solder bumps provided on a lower major surface of the substrate, a semiconductor chip provided on an upper major surface of the substrate, a resin package body provided on the upper major surface of the substrate so as to bury the semiconductor chip ther ...


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W Thomas Novak, Zahirudeen Premji, Uday G Nayak, Akimitsu Ebihara: Precision motion stage with single guide beam and follower stage. Nikon Precision, Norman R Klivans, Skjerven Morrill MacPherson Franklin & Friel, April 29, 1997: US05623853 (402 worldwide citation)

An XY stage for precision movement for use in aligning a wafer in a microlithography system. A main stage supporting the wafer straddles a movable beam that is magnetically driven in a first linear direction in the XY plane. A follower stage, mechanically independent of the main stage, also moves in ...


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Mark A Saab: Heat transfer catheters and methods of making and using same. Lappin & Kusmer, April 29, 1997: US05624392 (380 worldwide citation)

Heat transfer catheter apparatus and methods of making and using same are disclosed wherein fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of therm ...


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Peter V W Loomis, Peter L Froeberg: Position reporting cellular telephone. Trimble Navigation, Thomas E Law Offices of Thomas E Schatzel A Prof Corporation Schatzel, April 29, 1997: US05625668 (344 worldwide citation)

A cellular telephone system embodiment of the present invention comprises a combination global positioning system (GPS) receiver and cellular transceiver and a data processing facility for converting latitude, longitude, velocity and bearing information provided by the GPS receiver into meaningful d ...