1
Winter Andreas Dr, Spaleck Walter Dr: Process for preparing 1-olefinpolymers.. Hoechst, February 8, 1989: EP0302424-A1 (108 worldwide citation)

In Ziegler catalysts based on a metallocene as the transition-metal component and on an aluminoxane as activator, preactivation of the metallocene by means of the aluminoxane results in a significant increase in the activity of the catalyst system. Furthermore, use of a catalyst system of this type ...


2
Minamida Isao, Iwanaga Koichi, Okauchi Tetsuo: Alpha-unsaturated amines, their production and use.. Takeda Chemical Industries, February 8, 1989: EP0302389-A2 (103 worldwide citation)

alpha -Unsaturated amines of the formula: wherein X and X are such that one is an electron-attracting group with the other being a hydrogen atom or an electron-attracting group; R is a group attached through a nitrogen atom; R is a hydrogen atom or a group attached through a carbon, nitrogen or oxyg ...


3
Strupczewski Joseph Thomas: 1-phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments.. Hoechst Roussel Pharma, February 8, 1989: EP0302423-A2 (84 worldwide citation)

The present invention relates to novel 1-phenyl-3-(1-piperazinyl)-1H-indazoles and intermediates and a process for the preparation thereof. The compounds according to the invention exhibit analgesic, anti-convulsive and anti-depressant activities, and can therefore be used as medicaments.


4
Androphy Elliot J, Lowy Douglas R, Schiller John T: Viral expression inhibitors.. New England Medical Center, February 8, 1989: EP0302758-A1 (68 worldwide citation)

A method of inhibiting the growth of a virus, the DNA of the virus including the nucleic acid sequence 5 min ACCXNNNPyCGGTXY3 min , where each N, X and Y is independently, any nucleotide, and Py is C or T, the nucleic acid sequence being capable of binding to a protein encoded by the DNA of the viru ...


5
Rubin David: Free fatty acids for treatment or prophylaxis of rheumatoid arthritis.. Century Lab, February 8, 1989: EP0302482-A2 (62 worldwide citation)

Eicosapentaenoic acid and docosahexaenoic acid, in free acid form or in the form of a pharmaceutically acceptable salt thereof, are useful in treating rheumatoid arthritis. The free fatty acids (or salts) were an order of magnitude more effective in treating arthritis than the same amount of EPA and ...


6
Tice Thomas R, Gilley Richard M: Drug delivery system and method of making the same.. Southern Res Inst, February 8, 1989: EP0302582-A1 (53 worldwide citation)

A compatible, biodegradable microcapsule delivery system for active ingredients, including hormonally active peptides, proteins, or other bioactive molecules, and a method of making the same. The ingredients are encapsulated in biodegradable copolymer excipients of varying mole ratios and the blend ...


7
Karp Alan Hersh: A method of controlling the use of computer programs.. Ibm, February 8, 1989: EP0302710-A2 (50 worldwide citation)

The copy protection of personal computer (PC) software distributed on diskettes is assisted by providing a unique identification (ID) stored in read only memory (ROM) of a personal computer in which software on a diskette is to be used. This ID is accessible to the user of the computer. A vendor who ...


8
Mattox John Robert: Microbicidal microemulsion.. Rohm & Haas, February 8, 1989: EP0302701-A2 (45 worldwide citation)

Dilution stable oil-in-water microemulsions of microbicidal isothiazolones of low water solubility can be formed by using certain polyoxyethylene/polyoxypropylene block copolymers together with anionic surfactant and specified cosurfactant.


9
Vanerden Donald L, Boeckmann Hugo: Reclosable bag having an outer reclosable zipper type closure and inner non-reclosable closure.. Minigrip Europe, February 8, 1989: EP0302144-A2 (45 worldwide citation)

A bag (65) has wall panels (67) defining a receptacle space (70) and providing a bag mouth (71) arrangement between upper end portions of the wall panels (67). A tamper evident, and if desired hermetic seal, non-reclosable closure (78) adjacent to a reclosable zipper (74) and located adjacently belo ...


10
Kato Masayasu, Toyoshima Yoshio, Iwano Norio: Production of 2-(2-pyridylmethylsulfinyl)-benzimidazole compounds.. Takeda Chemical Industries, February 8, 1989: EP0302720-A1 (41 worldwide citation)

2-(2-pyridylmethylsulfinyl)benzimidazole compounds are produced by subjecting 2-(2-pyridylmethylthio)benzimidazole compounds to oxidation with hydrogen peroxide in the presence of vanadium compounds in good yield and with low production of by-products.



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