Carini David John, Duncia John Jonas Vytautas: Angiotensin ii receptor blocking imidazoles.. Du Pont, January 20, 1988: EP0253310-A2 (316 worldwide citation)

Substituted imidazoles such as are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.

Wenderoth Bernd Dr, Rentzea Costin Dr, Ammermann Eberhard Dr, Pommer Ernst Heinrich Dr, Steglich Wolfgang Prof Dr, Anke Timm Prof Dr: Oximethers and fungicides containing them.. BASF, January 20, 1988: EP0253213-A1 (166 worldwide citation)

Oximether der Formel in der R und R Wasserstoff oder Alkyl, X (m = 1 bis 5) Halogen, Cyano, Trifluormethyl, Nitro, Alkyl, Alkoxy, gegebenenfalls substituiertes Phenyl, Phenoxy, Benzyloxy oder Wasserstoff und Y Methylenoxy, Oxymethylen, Ethylen, Ethenylen, Ethinylen oder Sauerstoff bedeutet, und dies ...

Sasaki Masayoshi: Semiconductor memory device.. Oki Electric, January 20, 1988: EP0253631-A2 (128 worldwide citation)

In a semiconductor memory device, a memory cell comprises a first MOS transistor (Q1) of a first channel type formed on a semiconductor substrate (21) and having a gate electrode (25) connected to a word line. A charge storage electrode 28 is connected to the drain (24) of the first transistor and f ...

Colin Michel, Guenard Daniel, Gueritte Voegelein Francoise, Potier Pierre: Taxol derivatives, their preparation and pharmaceutical compositions containing them.. Rhone Poulenc Sante, January 20, 1988: EP0253738-A1 (112 worldwide citation)

Nouveaux dérivés du taxol de formule générale (I) dans laquelle R représente hydrogène ou acétyle, un des symboles R1 ou R2 représente hydroxy et l'autre représente tertiobutoxycarbonylamino et leurs isomères, leur préparation et les compositions phamaceutiques qui les contiennent

Klaus Michael Dr, Weiss Ekkehard Dr: Tetrahydronaphthalène and indane derivatives, their synthesis and application in pharmaceutical preparations.. Hoffmann La Roche, January 20, 1988: EP0253302-A2 (110 worldwide citation)

Die Verbindungen der allgemeinen Formel worin X und Y -CH2- oder >C(CH3)2; Z einen Rest -CHR-, >CO, >CROR, -CHR-CHR-, -CHOR-CH2-, -CO-CHOR- oder -CHOR-CHOR- darstellt; R einen 5- oder 6-gliedrigen, mono-cyclisch-heterocyclischen Rest darstellt, der durch Halogen, nieder-Alkyl, nieder-Alkoxy, Acyloxy ...

Oshlack Benjamin: Controlled release bases for pharmaceuticals.. Euro Celtique, January 20, 1988: EP0253104-A1 (105 worldwide citation)

The release of therapeutically active agents from controlled release bases is extended by using a combination of a higher aliphatic alcohol and an acrylic resin as the base material.

Tucker Howard: Substituted anilides having antiandrogenic properties.. Ici, January 20, 1988: EP0253503-A2 (94 worldwide citation)

An acylanilide of the formula:- wherein R or R which may be the same or different, each is an electron-withdrawing substituent, alkylthio or phenylthio or R is hydrogen, alkyl or alkoxy; wherein R is hydrogen or halogen; wherein R is hydrogen or alkyl, or is joined to R as stated below: wherein R is ...

Colin Michel, Guenard Daniel, Gueritte Voegelein Francoise, Potier Pierre: Process for the preparation of taxol and of desacetyl-10-taxol.. Rhone Poulenc Sante, January 20, 1988: EP0253739-A1 (80 worldwide citation)

Procédé de préparation du taxol et du désacétyl-10 taxol à partir d'un produit de formule générale (I) dans laquelle R' représente un radical acétyle ou trichloro-2,2,2 éthoxycarbonyle.

Upton Gertrude Virginia: Combination dosage form for premenopausal women.. American Home Prod, January 20, 1988: EP0253607-A1 (66 worldwide citation)

Disclosed herein is a method of providing hormonal replacement therapy and contraception for a pre-menopausal woman, which comprises administering to a pre-menopausal woman in need thereof a combination dosage form of an estrogen selected from 0.5-2.0 mg. of 17 beta -estradiol, 0.008-0.030 mg. of et ...

Hellstrom Karl Erik, Hellstrom Ingegerd E, Lavie Efraim: Novel immunoconjugates and methods for their use in tumor therapy.. Oncogen, January 20, 1988: EP0253202-A2 (66 worldwide citation)

Novel pH-sensitive immunoconjugates which dissociate in low-pH tumor tissue, comprising a chemotherapeutic agent and an antibody reactive with a tumor-associated antigen are described. The chemotherapeutic agent is coupled to the antibody by a link which is unstable in low pH. The link may comprise ...