Sumanas Rakhit: Acyl derivatives of rapamycin. Ayerst McKenna and Harrison, Arthur E Wilfond, February 23, 1982: US04316885 (224 worldwide citation)

Disclosed are monoacyl and diacyl derivatives of rapamycin, processes for their preparation, methods of using the derivatives and pharmaceutical compositions of the derivatives. The derivatives are useful, inter alia, as antifungal antibiotics.

Herman R Weed, Ram M Engira: Remote position and orientation detection employing magnetic flux linkage. Ohio State University Research Foundation, Millard & Cox, February 23, 1982: US04317078 (221 worldwide citation)

The process and system for locating the position and orientation of an implement in space wherein a varying magnetic field responsive component (14) such as a coil is positioned upon the implement. A magnetic field source (12) excitable from an a.c. source derives alternating flux fields which are m ...

Nikolai N Kapitanov: Surgical apparatus for suturing soft tissues with lengths of suturing material with spicules. McAulay Fields Fisher Goldstein & Nissen, February 23, 1982: US04316469 (202 worldwide citation)

A surgical apparatus for suturing soft tissues with lengths of suturing material with spicules comprises at least one hollow needle, mounted in the apparatus body, with a bore to accommodate a length of suturing material, introduced into the tissue to be sutured together with the needle, as well as ...

Henri J Marais, Kevin M Morrison: Intravenous vascular stabilizer. Barlow & Barlow, February 23, 1982: US04316461 (163 worldwide citation)

This invention provides a vascular stabilizer in which a base plate that has a major medial longitudinal aperture or slot is adapted to be positioned so that the edges of the slot embrace a vein. The slot is defined by an arched connector or hood portion to rigify the slot and to protect a needle-ty ...

Joseph I Masters, Gershon M Goldberg, Jerome M Lavine: Surface sensitized chalcogenide product and process for making and using the same. Ionomet Company, Frank A Steinhilper, February 23, 1982: US04316946 (154 worldwide citation)

Surface sensitization of a chalcogenide glass is achieved by depositing an extremely thin silver layer, for example, by depositing a silver halide and developing and fixing in the absence of exposure. The sensitized chalcogenide can then be exposed to light to make it etch-resistant. Further exposur ...

Erik O Giese, Alexander L Gross: Athletic shoe construction. Comfort Products, Pennie & Edmonds, February 23, 1982: US04316335 (138 worldwide citation)

An athletic shoe which has a light-weight and readily flexible sole construction including shock absorbing portions in the heel and forefoot areas of the sole having different shock absorbing porperties with the shock absorbing portion in the heel area having a shock absorbing property greater than ...

Mieczyslaw Mirowski, Morton M Mower, Alois A Langer: Cardioverting device with stored energy selecting means and discharge initiating means, and related method. Mieczyslaw Mirowski, Fleit & Jacobson, February 23, 1982: US04316472 (132 worldwide citation)

An externally controlled implantable electronic device for delivering a cardioverting pulse of energy to the atrium of an ailing heart. In one embodiment, the device is particularly suited for use when the patient visits the office of his physician, and contemplates the transmission of both informat ...

Jeffrey R Teza, Kenneth A Lies: Four mode microcomputer power save operation. Texas Instruments Incorporated, Leo Heiting, Robert D Marshall Jr, Melvin Sharp, February 23, 1982: US04317181 (126 worldwide citation)

A calculator having constant memory utilizing a low power microcomputer with on-chip memory capability, and multiple partition power control of circuit groups. Incorporation of a first and second switched negative voltage and a non-switched negative voltage enables the power hungry clocked logic and ...

Robert S Dotson Jr: Ophthalmic handpiece with pneumatically operated cutter. February 23, 1982: US04316465 (125 worldwide citation)

An ophthalmic handpiece is disclosed. The handpiece includes coaxial irrigation and aspiration needles, with passageways through the body of the handpiece for connection to conventional equipment for supplying irrigation and aspiration. Within the aspiration needle, there is a reciprocating cutting ...

Kenneth A Lies: Clocked logic low power standby mode. Texas Instruments Incorporated, Robert D Marshall Jr, Leo N Heiting, Melvin Sharp, February 23, 1982: US04317180 (124 worldwide citation)

An electronic data processing system such as utilized in battery powered hand held calculators having a two mode clock control for control of power consumption. A power consumption controller enables generation of clock signals in an active cycling state for operating the data processing system in a ...

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