1
Tamaki Kazuhiko, Yamaguchi Takahiro, Oda Kozo, Terasaka Naoki, Nakai Daisuke, Nakadai Masakazu: (Ja) 2以上の置換基を有するベンゼン化合物, (En) Benzene compound having 2 or more substituents. Daiichi Sankyo Company, Tamaki Kazuhiko, Yamaguchi Takahiro, Oda Kozo, Terasaka Naoki, Nakai Daisuke, Nakadai Masakazu, YAGUCHI Toshiaki, May 4, 2006: WO/2006/046593 (45 worldwide citation)

(EN) Disclosed is an excellent LXR modulator. Specifically disclosed is a compound represented by the general formula (I) below or the like. (I) [In the formula, R1 represents a -COR9 (wherein R9 represents an alkyl, optionally substituted alkoxy or optionally substituted amino); R2 represents an H, ...


2
Oizumi Kiyoshi, Naito Satoru, Nakao Akira, Shinozuka Tsuyoshi, Matsui Satoshi, Shimada Kousei: (Ja) チエノピリジン誘導体, (En) Thienopyridine derivatives. Sankyo Company, Oizumi Kiyoshi, Naito Satoru, Nakao Akira, Shinozuka Tsuyoshi, Matsui Satoshi, Shimada Kousei, YAGUCHI Toshiaki, October 27, 2005: WO/2005/100365 (24 worldwide citation)

(EN) The invention provides osteogenesis-promoting compounds, namely, compounds represented by the general formula (I) and pharmacologically acceptable salts thereof: wherein R1 is H or alkyl; R2 is RaS-, RaO-, RaNH-, Ra(Rb)N-, or cyclic amino; and Ra and Rb are each optionally substituted alkyl, op ...


3
Hayakawa Ichiro, Yoshida Masao, Sugano Yuichi, Kurata Hitoshi, Tanimoto Tatsuo, Karasawa Hiroshi, Kohama Takafumi, Uto Yoshikazu: (Ja) 置換されたウレア化合物, (En) Substituted ureas. Sankyo Company, Hayakawa Ichiro, Yoshida Masao, Sugano Yuichi, Kurata Hitoshi, Tanimoto Tatsuo, Karasawa Hiroshi, Kohama Takafumi, Uto Yoshikazu, YAGUCHI Toshiaki, February 23, 2006: WO/2006/019020 (17 worldwide citation)

(EN) Urea derivatives having excellent DGAT inhibiting activity or pharmacologically acceptable salts thereof, namely, urea derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 is C6-10 aryl which may be substituted with one member selected ...


4
KURATA Hitoshi, UTO Yoshikazu, FUJIBAYASHI Yuko, KOHAMA Takafumi, TANIMOTO Tatsuo, KARASAWA Hiroshi: [ja] ウレア誘導体, [fr] DÉRIVÉ D’URÉE, [en] UREA DERIVATIVE. KURATA Hitoshi, UTO Yoshikazu, FUJIBAYASHI Yuko, KOHAMA Takafumi, TANIMOTO Tatsuo, KARASAWA Hiroshi, SANKYO COMPANY, YAGUCHI Toshiaki, January 12, 2006: WO/2006/004200 (16 worldwide citation)

[en] A urea derivative having excellent DGAT inhibitory activity or a pharmacologically acceptable salt thereof. The urea derivative is represented by the general formula (I) (II) (III) (XXXIX) (XL) [wherein R1 is, e.g., C6-10 aryl optionally substituted independently by one to five groups selected ...


5
Nishi Takahide, Nakamura Tsuyoshi, Sekiguchi Yukiko, Mizuno Yumiko, Shimozato Takaichi, Nara Futoshi: (Ja) ヘテロ環化合物, (En) Heterocyclic compound. Daiichi Sankyo Company, Nishi Takahide, Nakamura Tsuyoshi, Sekiguchi Yukiko, Mizuno Yumiko, Shimozato Takaichi, Nara Futoshi, YAGUCHI Toshiaki, November 2, 2006: WO/2006/115188 (16 worldwide citation)

(EN) Disclosed is a novel low toxic compound having an excellent immunosuppressive action or a pharmacologically acceptable salt thereof. Specifically disclosed is a compound represented by the general formula (I) below, a pharmacologically acceptable salt thereof or a pharmacologically acceptable p ...


6
Nishi Takahide, Shimozato Takaichi, Kagari Takashi, Doi Hiromi: (Ja) ppar調節剤を含有する医薬組成物, (En) Cyclic amine derivative containing ppar regulator. Daiichi Sankyo Company, Nishi Takahide, Shimozato Takaichi, Kagari Takashi, Doi Hiromi, YAGUCHI Toshiaki, December 28, 2006: WO/2006/137509 (11 worldwide citation)

(EN) It is intended to provide a pharmaceutical composition which is excellent as an agent for preventing or treating a disease related to an immunological action such as an autoimmune disease. The pharmaceutical composition comprises one or more members selected from the group consisting of PPAR re ...


7
Nishi Takahide, Shimozato Takaichi, Kagari Takashi, Doi Hiromi: (Ja) 免疫抑制剤としての医薬組成物, (En) Medicinal composition as immunosuppressant. Sankyo Company, Nishi Takahide, Shimozato Takaichi, Kagari Takashi, Doi Hiromi, YAGUCHI Toshiaki, February 2, 2006: WO/2006/011554 (8 worldwide citation)

(EN) A medicinal composition useful as an excellent preventive or therapeutic agent for diseases relating to immunization. The medicinal composition comprises at least one member selected from the group consisting of HMG-CoA reductase inhibitors and at least one member selected from the group consis ...


8
Takaishi Kiyosumi, Tsuji Makoto, Karasawa Hiroshi, Uto Yoshikazu: (Ja) 置換されたウレア誘導体を含有する医薬, (En) Pharmaceutical comprising substituted urea derivative. Daiichi Sankyo Company, Takaishi Kiyosumi, Tsuji Makoto, Karasawa Hiroshi, Uto Yoshikazu, YAGUCHI Toshiaki, July 5, 2007: WO/2007/074753 (4 worldwide citation)

(EN) Disclosed is a pharmaceutical comprising an urea derivative having an excellent anorexigenic effect or a pharmacologically acceptable salt thereof as an active ingredient. The pharmaceutical is an anoerxigenic agent and/or an appetite suppressant which comprises an urea derivative represented b ...


9
KAWASAKI Takao, SUZUKI Nobuyuki, YADA Shuichi: [ja] チアゾリジンジオン化合物を含有する医薬組成物, [fr] COMPOSITION PHARMACEUTIQUE CONTENANT UN COMPOSÉ DE THIAZOLIDINEDIONE, [en] PHARMACEUTICAL COMPOSITION CONTAINING THIAZOLIDINEDIONE COMPOUND. KAWASAKI Takao, SUZUKI Nobuyuki, YADA Shuichi, DAIICHI SANKYO COMPANY, YAGUCHI Toshiaki, January 18, 2007: WO/2007/007656 (3 worldwide citation)

[en] It is intended to provide a pharmaceutical composition which contains a thiazolidinedione compound and is excellent in drug absorbability. The pharmaceutical composition is a pharmaceutical composition in which cellulose, a cellulose derivative, a polyvinyl alcohol derivative, a polyvinyl alcoh ...


10
YAMAGUCHI Takahiro, YOSHIDA Masayuki, TAMAKI Kazuhiko: [ja] 置換ベンゼン化合物, [fr] COMPOSÉ DU BENZÈNE SUBSTITUÉ, [en] SUBSTITUTED BENZENE COMPOUND. YAMAGUCHI Takahiro, YOSHIDA Masayuki, TAMAKI Kazuhiko, SANKYO COMPANY, YAGUCHI Toshiaki, January 12, 2006: WO/2006/003923 (3 worldwide citation)

[en] Disclosed is an excellent LXR modulator. Specifically disclosed are compounds represented by the following general formula (I). (In the formula, R1 represents -COR9 (wherein R9 represents an alkyl, an optionally substituted alkoxy or an optionally substituted amino or the like), an optionally s ...