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Carolina Rubio de Hita, David van den Akker, Erik C E Govaers, Frank M J Platteau, Kurt Van Deun, Melissa Macpherson, Peter de Bie, Sophie Laviolette: Natural language information retrieval system and method. Novell, James H Morris, Alan B Sherr, Wolf Greenfield & Sack P C, June 27, 2000: US06081774 (496 worldwide citation)

An information retrieval system that represents the content of a language-based database being searched as well as the user's natural language query. In accordance with one aspect of the invention, the information retrieval system includes a non-real-time development system for automatically creatin ...


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Kevin Pojasek, Rahul Raman, Ram Sasisekharan: Rationally designed polysaccharide lyases derived from chondroitinase B. Massachusetts Institute of Technology, Wolf Greenfield & Sack P C, November 8, 2005: US06962699 (36 worldwide citation)

The invention relates to rationally designed polysaccharide lyases and uses thereof. In particular, the invention relates to modified chondroitinase B. The modified chondroitinase B enzymes of the invention are useful for a variety of purposes, including cleaving and sequencing polysaccharides such ...


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Mary Collins, Clive R Wood, Beatriz M Carreno, Deborah Luxenberg, Jason Jussif, Laura L Carter, Frances K Bennett, Viia Valge Archer, John Andrews, Caroline Russell: Methods of upmodulating adaptive immune response using anti-PD-1 antibodies. MedImmune, Wyeth, Wolf Greenfield & Sack P C, April 21, 2009: US07521051 (26 worldwide citation)

This disclosure provides antibodies and antigen-binding fragments that can act as agonists and/or antagonists of PD-1 (Programmed Death 1), thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The disclosed compositions and methods may be used for exampl ...


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Jonathan M Rothberg, Susan A Alie, Keith G Fife, Nevada J Sanchez, Tyler S Ralston: Microfabricated ultrasonic transducers and related apparatus and methods. Butterfly Network, Wolf Greenfield & Sack P C, June 30, 2015: US09067779 (25 worldwide citation)

Micromachined ultrasonic transducers integrated with complementary metal oxide semiconductor (CMOS) substrates are described, as well as methods of fabricating such devices. Fabrication may involve two separate wafer bonding steps. Wafer bonding may be used to fabricate sealed cavities in a substrat ...


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Mark LaMantia: Crib and playpen protective enclosure. Wolf Greenfield & Sack P C, March 1, 2005: US06859958 (24 worldwide citation)

An enclosure for a crib or playpen includes a dome-shaped top and a box-shaped bottom structure completely enclosing the interior of a crib or playpen. The enclosure includes a flap in the dome-shaped top to allowing a parent or guardian to easily place a child in or remove a child from the crib or ...


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Russell L Rivin, Lori A Bellavance: Non-intrusive application code profiling method and apparatus. Analog Devices, Wolf Greenfield & Sack P C, April 6, 2004: US06718286 (12 worldwide citation)

System and method for monitoring a processor when it executes software code for a computer program. A register collects information regarding instructions executed by the processor, from the program counter; and a sampler, operatively connected to the register, asynchronously from the operation of t ...


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Wolfgang Gschwendtner: Synchronise an audio cursor and a text cursor during editing. Nuance Communications Austria, Wolf Greenfield & Sack P C, February 14, 2012: US08117034 (9 worldwide citation)

A speech recognition device (1) processes speech data (SD) of a dictation and thus establishes recognized text information (ETI) and link information (LI) of the dictation. In a synchronous playback mode of the speech recognition device (1), during the acoustic playback of the dictation a correction ...


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Jeffrey T Black, Jeffrey A Weiss: Method and apparatus for providing a variable reset interval in a transmission system for encoded data. Telco Systems, Wolf Greenfield & Sack P C, February 3, 1998: US05715260 (8 worldwide citation)

A method and apparatus for reducing the amount of corrupted data in a system for transmitting encoded data across a network, which system requires sychronization between encoding and decoding nodes, the method and apparatus involving (a) providing an indication of the reliability of the channel betw ...


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Richard Franklin Eilbert: Methods and apparatus for e-beam scanning. L 3 Communications Security and Detection Systems, Wolf Greenfield & Sack P C, September 23, 2008: US07428297 (7 worldwide citation)

In one aspect, an x-ray scanning device is provided. The x-ray scanning device comprises a target adapted to convert electron-beam (e-beam) energy into x-ray energy, a detector array positioned to detect at least some x-rays emitted from the target, and a conveyer mechanism adapted to convey items t ...