1
Banerjee Amit: Compounds and methods for the treatment of ubiquitin conjugating disorders. Hygeia Biological Systems, Banerjee Amit, WILLIAMS Kathleen M, February 23, 2006: WO/2006/020681 (22 worldwide citation)

The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, s ...


2
Liew Choong Chin: Method for the detection of gene transcripts in blood and uses thereof. Genenews, Williams Kathleen M, Liew Choong Chin, WILLIAMS Kathleen M, December 29, 2004: WO/2004/112589 (18 worldwide citation)

The present invention relates generally to the identification of biomarkers of conditions including disease and non disease conditions as well as identifying compositions of biomarkers. The invention further provides a method of diagnosing disease, monitoring disease progression, and differentially ...


3
Lowe David A, Cummings Christopher J, Keonig Gerhard: Transgenic flies expressing mutant a&bgr;42. Envivo Pharmaceuticals, Lowe David A, Cummings Christopher J, Keonig Gerhard, WILLIAMS Kathleen M, May 12, 2005: WO/2005/041650 (10 worldwide citation)

The present invention discloses a transgenic fly that expresses the Iowa mutant version of the human A&bgr;42 peptide of human amyloid-&bgr; precursor protein (APP), and a double transgenic fly that expresses both the Tau protein and the human A&bgr;Iowa peptide of human amyloid-&bgr; precursor prot ...


4
Arezi Bahram, Hogrefe Holly, Sorge Joseph A, Hansen Connie Jo: Dna polymerase mutants with reverse transcriptase activity. Stratagene, Arezi Bahram, Hogrefe Holly, Sorge Joseph A, Hansen Connie Jo, WILLIAMS Kathleen M, May 13, 2004: WO/2004/039947 (8 worldwide citation)

The present invention relates to compositions and kits comprising a mutant DNA polymerase with increased reverse transcriptase activity. The invention also relates to methods for using the subject compositions and kits.


5
Cardineau Guy A, Mason Hugh Stanley, Vaneck Joyce M, Kirk Dwayne D, Walmsley Amanda Maree: Vectors and cells for preparing immunoprotective compositions derived from transgenic plants. Boyce Thompson Institute For Plant Research, Dow Agrosciences, Cardineau Guy A, Mason Hugh Stanley, Vaneck Joyce M, Kirk Dwayne D, Walmsley Amanda Maree, WILLIAMS Kathleen M, November 18, 2004: WO/2004/098533 (6 worldwide citation)

The invention is drawn towards vectors and methods useful for preparing genetically transformed plant cells that express immunogens from pathogenic organisms which are used to produce immunoprotective particles useful in vaccine preparations. The invention includes plant optimized genes that encode ...


6
Sorge Joseph A, Hogrefe Holly, Hansen Connie Jo, Arezi Bahram, Mullinax Rebecca Lynn: Compositions and methods for synthesizing cdna. Stratagene California, Sorge Joseph A, Hogrefe Holly, Hansen Connie Jo, Arezi Bahram, Mullinax Rebecca Lynn, WILLIAMS Kathleen M, December 15, 2005: WO/2005/118866 (5 worldwide citation)

The present invention relates to composition, kits and methods comprising a mutant DNA 5 polymerase exhibiting increased reverse transcriptase activity. The invention also relates to methods of generating modified cDNA.


7
Church George M: Replica amplification of nucleic acid arrays. President & Fellows Of Harvard College, Church George M, WILLIAMS Kathleen M, April 22, 1999: WO/1999/019341 (5 worldwide citation)

A method of producing a plurality of a nucleic acid array, comprising, in order, the steps of amplifying $i(in situ) nucleic acid molecules of a first randomly-patterned, immobilized nucleic acid array comprising a heterogeneous pool of nucleic acid molecules affixed to a support, transferring at le ...


8
Boeckeler Matthew, Chavez Bryan, Cummings Christopher J, Singh Carol M, Low Thomas P, Crittenden Max, Shimon Jeff: Device and method for automated transfer of small organisms. Envivo Pharmaceuticals, Boeckeler Matthew, Chavez Bryan, Cummings Christopher J, Singh Carol M, Low Thomas P, Crittenden Max, Shimon Jeff, WILLIAMS Kathleen M, March 8, 2007: WO/2007/027635 (4 worldwide citation)

A device is disclosed for transferring an organism from a donor container to a recipient container. The device comprises a transfer plate assembly comprising a first subassembly and a second subassembly. The transfer plate assembly positions donor containers and recipient containers in an inverted r ...


9
Lorbert Steve, Wu Jennifer, Uraizee Farooq, Schasteen Charles Steven: Methionine recovery processes. Novus Internation, Lorbert Steve, Wu Jennifer, Uraizee Farooq, Schasteen Charles Steven, WILLIAMS Kathleen M, January 27, 2005: WO/2005/007862 (4 worldwide citation)

The present invention relates to a method of making a methionine preparation, for example for an animal feed additive. The invention also related to methods for increasing the solubility of a methionine preparation.


10
Tai Isabelle T, Chen Lan Bo: Cancer therapy sensitizer. Dana Farber Cancer Institute, Tai Isabelle T, Chen Lan Bo, WILLIAMS Kathleen M, August 5, 2004: WO/2004/064785 (4 worldwide citation)

The present invention relates to compositions and methods for sensitizing cancer therapy. The invention provides such compositions comprising a SPARC family polypeptide or polynucleotide, as well as recombinant cells containing a SPARC family polypeptide or polynucleotide. The compositions and metho ...